A5014924665- vaccines and immunoinformatics approaches
- Tuberculosis Research and Epidemiology
- Immunotherapy and Immune Responses
- Stress Responses and Cortisol
- High-Energy Particle Collisions Research
- Adolescent and Pediatric Healthcare
- Pancreatic function and diabetes
- Particle physics theoretical and experimental studies
- Diet, Metabolism, and Disease
- SARS-CoV-2 and COVID-19 Research
- Diabetes and associated disorders
- Tryptophan and brain disorders
- Particle Detector Development and Performance
Chinese PLA General Hospital
2024
Hunan Normal University
2019
Hunan Provincial People's Hospital
2019
IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide. Current studies have shown that Th17/Treg immune balance may be involved in occurrence of IgAN, but exact mechanism still unclear. Indoleamine 2,3-dioxygenase (IDO) an enzyme catalyses degradation tryptophan (Trp) through kynurenine (Kyn) pathway; it can control inflammation and response by inducing Trp starvation. IDO a key molecule regulating balance. However, not clear whether IgAN disease In this study, mouse model...
Background: Vaccination is one of the effective measures to prevent latent tuberculosis infection (LTBI) from developing into active (TB). Applying bioinformatics methods pre-evaluate biological characteristics and immunogenicity vaccines can improve efficiency vaccine development. Objectives: To evaluate W541 explore application technology in research. Methods: This study concatenated immunodominant sequences Ag85A, Ag85B, Rv3407, Rv1733c construct DNA vaccine. Then, were used analyze...
ABSTRACT Background Vaccination is one of the effective measures to prevent latent tuberculosis infection (LTBI) from developing into active (TB). Applying bioinformatics methods pre‐evaluate biological characteristics and immunogenicity vaccines can improve efficiency vaccine development. Objectives To evaluate TB W541 explore application technology in research. Methods This study concatenated immunodominant sequences Ag85A, Ag85B, Rv3407 , Rv1733c construct DNA vaccine. Then, were used...