A5005301824- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiology practices and education
- Radioactivity and Radon Measurements
- Medical Imaging Techniques and Applications
- NMR spectroscopy and applications
- Medical Image Segmentation Techniques
- Advanced NMR Techniques and Applications
- Cell Image Analysis Techniques
- Orthopedic Surgery and Rehabilitation
- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Multiple Sclerosis Research Studies
- Brain Tumor Detection and Classification
- Research Data Management Practices
- Tendon Structure and Treatment
- RFID technology advancements
- Ultrasound Imaging and Elastography
- Open Source Software Innovations
- Open Education and E-Learning
- Power Quality and Harmonics
- MRI in cancer diagnosis
- Neurogenesis and neuroplasticity mechanisms
Kelowna General Hospital
2023
University of British Columbia
2006-2023
Interior Health
2011-2023
Okanagan University College
2015-2021
University of Calgary
2007-2017
Diagnostic Services Manitoba
2015
BC Cancer Agency
2014
Vancouver Coastal Health
2010-2011
Objective To analyze the texture of T2‐weighted magnetic resonance imaging (MRI) postmortem multiple sclerosis (MS) brain, and to determine whether how MRI correlates with tissue pathology. Methods Ten brain samples from 3 subjects MS were examined. Areas complete, partial, or no loss Luxol fast blue (myelin) Bielschowsky (axons) staining marked on histological images, matched corresponding as lesions, diffusely abnormal white matter (DAWM), normal‐appearing (NAWM). The number CD45 + cells...
Abstract In vitro experiments on 15 white matter samples from five bovine brains were performed a 1 H‐NMR spectrometer at 24°C and 37°C. The average myelin water fractions (MWFs) 10.9% 11.8% for 37°C, respectively. T relaxation time 37°C was found to be 830 ms, exhibiting monoexponential behavior. A four‐pool model including intra/extracellular (IE) water, nonmyelin tissue, tissue proposed simulate the NMR behavior of matter. cross‐relaxation correction introduced compensate shifting...
Abstract Water exchange can play an important role in interpreting compartment‐specific magnetic resonance imaging data brain. For example, MR method of myelin measurement, known as water fraction imaging, assumes that processes are slow compared with the measurement time scale. In this article, we examined whether have effect on values. A previously established four pool model white matter was used to simulate interactions between two aqueous compartments (myelin and intra/extracellular...
The desire to monitor the spatial-temporal characteristics of myelination in spinal cord (SC), context pathological change demyelinating diseases or proposed neuroregenerative protocols, has led an interest noninvasive image-based myelin measurement methods. We present one strategy: a magnetic resonance-based measure that capitalizes on T(2) relaxation water compartmentalized within tissue. In this study, 32-echo studies for measuring fraction (MWF) were applied healthy control SC vivo using...
Abstract Typical quantitative T 2 (q ) analysis involves creating distributions using a regularized algorithm from region‐of‐interest averaged decay data. This study uses q of simulated and experimental signals to determine how (a) noise‐type, (b) regularization, (c) versus multivoxel analyses affect distributions. Our simulations indicate that regularization causes myelin water fraction intra/extracellular geometric mean underestimation worsens as the signal‐to‐noise ratio decreases. The...
Abstract T 2 was used in this study to assess tendon microstructure. Two unloaded digital extensor tendons were bent such that their long axes imaged throughout 180° with respect B 0 . ‐weighted images reveal periodic banding (∼200 μm) when oriented at ±55° Five pairs of the influence load on T2W MRI: one each pair loaded a 7.8‐N mass, and both fixed formalin then 55° MRI present unloaded, but not loaded, tendons. In tendons, polarized‐light microscopy revealed collagen crimp periodicity...
The aim of this study was to establish an advanced analytical platform for complex in vivo pathologies. We have developed a software program, QuantitativeT2, voxel-based real-time quantitative T2 magnetic resonance imaging. analyzed murine brain tumors confirm feasibility our method neurological conditions. Anesthetized mice (with invasive gliomas, and controls) were imaged on 9.4 Tesla scanner using Carr-Purcell-Meiboom-Gill sequence. multiecho decays from axial slices QuantitativeT2....
Abstract When performing multiexponential analysis of relaxation times in the slow exchange regime, it is often convenient to simplify resulting distribution one or more time constants. In doing so, what averaging method should be used and rate constant reported? This note outlines why geometric mean most appropriate provides a proof that constants are reciprocals, which counter‐intuitive unless considers values different than physically species. © 2011 Wiley Periodicals, Inc. Concepts Magn...
In x-ray based imaging of the breast, contrast between fibroglandular (Fg) tissue and adipose (Ad) is a source anatomic noise. The goal this work was to validate by simulation experiment mathematical framework for modelling Fg component noise in digital mammograpy (DM) dual-energy (DE) DM. Our unifies generalizes existing approaches. We compared predictions directly with empirical measurements power spectrum CIRS BR3D structured breast phantom using two clinical mammography systems four beam...
In 2013 Health Canada conducted a national survey of computed tomography (CT) radiation usage. We analysed contributions from all 7 public health authorities in the province British Columbia, which covered scanner age, number slices, and common adult protocols (≥ 19 years: 70 ± 20 kg, head, chest, abdomen/pelvis, trunk). Patient doses were recorded for protocols. Diagnostic reference levels (DRLs) was calculated using data with >10 patient each protocol. Data based on image reconstruction...
X-ray regulations and room design methodology vary widely across Canada. The Canadian Organization of Medical Physicists (COMP) conducted a survey in 2016/2017 to provide useful snapshot existing variations rules methodologies for human patient medical imaging facilities. Some jurisdictions no longer have radiation safety regulatory requirements COMP is concerned that lack oversight might erode safe practices. Harmonized standards will facilitate ensure continued attention given public...
Digital documents provide too many benefits to turn back now. With hand-held devices becoming more powerful all the time, literature reviews of future will be earned around in your pocket, "with multiple copies synchronized and easily backed up anywhere. The review has become paper less, replacing with pdf files, filing cabinets reference managers, notebooks tagclouds. is now paperless, portable, browsable, searchable.
This technical note demonstrates computed tomography (CT) radiation profile measurement using radiography (CR) imaging plate raw data showing it is possible to perform the CT collimation width a single scan without saturating plate. Previously described methods require careful adjustments CR reader settings in order avoid signal clipping processed image. measurements were taken as part of routine quality control on 14 scanners from four vendors. cassettes placed scanner bed, raised...
Motivation: RF coil failures are often not visually recognizable. Quality control is only done weekly or monthly, leading to days weeks where diagnostic images may be negatively impacted. Goal(s): Identify on patient using deep transfer learning. Approach: >10,000 passed and failed from 50 patients were used train 4 pre-trained learning models 2 different pipelines: (1) shuffled all into test, (2) by each patients’ images. Results: EfficientNet V2 (L) was the highest...
Healthcare outcomes are intrinsically tied to the quality of medical imaging, which, in turn, relies on precision devices such as Computed Tomography (CT) scanners. Ensuring high images necessitates routine manual control testing, a process known for its time-consuming, error-prone, and costly nature. This paper presents study that evaluates state-of-the-art deep convolutional neural network models automate images. We evaluate performance 5 different wherein InceptionResNetV2 achieves best...