A5029455193- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Ear and Head Tumors
- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- Traumatic Ocular and Foreign Body Injuries
- Genetic Syndromes and Imprinting
- Hedgehog Signaling Pathway Studies
- Retinal and Optic Conditions
- Cervical Cancer and HPV Research
- GDF15 and Related Biomarkers
- Diet and metabolism studies
- Genetic and Kidney Cyst Diseases
- Vasculitis and related conditions
- Meningioma and schwannoma management
- Metabolism, Diabetes, and Cancer
- Head and Neck Surgical Oncology
Mayo Clinic
2023-2025
WinnMed
2024
Mayo Clinic in Arizona
2023-2024
University of Florida
2022-2023
Abstract Objective Margin distance is a significant prognosticator in oral cavity cancer but its role HPV‐related oropharyngeal squamous cell carcinoma [HPV(+)OPSCC] remains unclear. Here, we investigate the impact of margin on locoregional recurrence HPV(+)OPSCC. Study Design This retrospective cohort study surgically treated HPV(+)OPSCC patients. Patients received either standard care (at least 60 Gy with or without cisplatin) de‐escalated adjuvant therapy (30‐36 concurrent docetaxel). was...
Abstract Objective To (1) track the incidence of pleomorphic adenomas (PAs) and (2) compare demographic treatment trends in PAs over last five decades a single county. Study Design Retrospective cohort all patients with pathologic diagnosis nonrecurrent PA from January 1976 to December 2022. Setting Olmsted County, Minnesota. Methods Incidence was calculated per 100,000 persons/year age sex‐adjusted US 2020 census data. were identified using Poisson rate regression models. Changes clinical...
Objective: To assess the impact of extent parotidectomy on surgical and oncologic outcomes in low grade mucoepidermoid carcinoma (LGMEC). Methods: A retrospective chart review all patients undergoing primary treatment for LGMEC from 2000 to 2022 was conducted. Clinical features collected included demographics, facial nerve function, operative techniques, postoperative complications/facial recurrence. Results: 58 were included; 10 underwent partial (PP), 38 superficial (SP), near-total/total...
Metformin, a frontline therapy for type 2 diabetes and related metabolic diseases, results in variable outcomes. This study aimed to investigate whether sweetened beverages (caloric or non-caloric) affect the therapeutic benefits of metformin on glucose, food intake, weight loss diet-induced obesity. Mice were given high-fat diet water 8 weeks induce obesity glucose intolerance. Then, mice randomized receive either water, high-fructose corn syrup (HFCS), non-nutritive sweetener saccharin 6...
Objective To report a fatal case of Susac syndrome in congenitally deaf patient with cochlear implant and history migraines, emphasizing the diagnostic challenges patients preexisting conditions. Patient A 33-year-old male congenital hearing loss, implant, chronic migraines who presented mild subacute auditory disturbance headaches that later progressed to severe encephalopathy. Intervention Explantation non–magnetic resonance imaging (MRI) compatible followed by MRI, fundoscopy,...
Abstract Objective The extent of parotidectomy for benign tumors has de‐escalated in the United States. We aim to define modern benchmarks operative time and hospital length stay (LOS) identify risk factors that may prolong these benchmarks. Study Design This is a retrospective cross‐sectional study all adults who underwent primary parotid neoplasm between January 2011 December 2021 using American College Surgeons National Surgical Quality Improvement Program database. Methods was defined...
Obesity is a cardinal feature of Bardet-Biedl syndrome (BBS), syndromic ciliopathy caused by mutations in genes for BBS 1-21. proteins control the function primary cilia that act as sensory antenna on virtually all mammalian cells. The mechanisms BBS-induced obesity remain poorly understood, resulting lack therapeutic options these patients. overarching goal study was to define underlying involved pathogenesis and use this knowledge identify novel targets. Given importance interoceptive...