A5059253267- Motor Control and Adaptation
- Action Observation and Synchronization
- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Tactile and Sensory Interactions
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Hemispheric Asymmetry in Neuroscience
- Transcranial Magnetic Stimulation Studies
- Advanced Neuroimaging Techniques and Applications
- Virtual Reality Applications and Impacts
- Muscle activation and electromyography studies
- Spatial Neglect and Hemispheric Dysfunction
- Neuroscience and Music Perception
- Parkinson's Disease Mechanisms and Treatments
- Hearing Loss and Rehabilitation
- Face Recognition and Perception
- Stroke Rehabilitation and Recovery
- Multisensory perception and integration
- Vestibular and auditory disorders
- Botulinum Toxin and Related Neurological Disorders
- Child and Animal Learning Development
- Visual perception and processing mechanisms
- Neurobiology of Language and Bilingualism
University of Otago
2016-2025
Brain Research New Zealand
2011-2014
Beijing Normal University
2014
University of California, Berkeley
1994-1997
Purdue University West Lafayette
1991-1992
Hartford Financial Services (United States)
1928
Kingswood Oxford
1928
The neural mechanisms of limb coordination were investigated by testing callosotomy patients and normal control subjects on bimanual movements Normal produced deviations in the trajectories when spatial demands for two hands different, despite temporal synchrony onset Callosotomy did not produce deviations, although their moved with but exhibited large increases planning execution time different relative to identical This dissociation indicates that interference results from callosal...
When the left and right hands produce 2 different rhythms simultaneously, coordination of is difficult unless can be integrated into a unified temporal pattern. In present study, authors investigated whether similar account applied to spatial domain. Participants (N = 8) produced movement trajectory semicircular form in single-limb bimanual conditions. tasks, 1 limb moved above other frontal plane. Bimanual tasks were constructed so that paths by limbs could easily conceptualized as parts...
The majority of investigations on coordinated action have focused temporal constraints in movements. Recent studies demonstrated spatial when the hands produce different trajectory shapes simultaneously. focus current study was to determine whether coupling occurs individual parameters actions, or per se undergo accommodation. Subjects were tested a bimanual paradigm investigate nature complex tasks. Shape and size required trajectories varied for two limbs. When that require assigned hands,...
Netrin-1 is a secreted protein that was first identified 20 years ago as an axon guidance molecule regulates midline crossing in the CNS. It plays critical roles various tissues throughout development and implicated tumorigenesis inflammation adulthood. Despite extensive studies, no inherited human disease has been directly associated with mutations NTN1, gene coding for netrin-1. Here, we have 3 exon 7 of NTN1 2 unrelated families 1 sporadic case isolated congenital mirror movements (CMM),...
Recent investigations of timing in motor control have been interpreted as support for the concept brain modularity. According to this concept, is organized into functional modules that contain mechanisms responsible general processes. Keele and colleagues (Keele & Hawkins, 1982; Ivry, 1987; Keele, Pokorny, Corcos, 1985) demonstrated within-subject variability in. cycle duration repetitive movements correlated across finger, forearm, foot movements, providing evidence a module. The present...
John Hughlings Jackson was a pioneer in neurology who thought deeply about the structure of brain and how that manifested itself various syndromes he saw clinic. He enunciated theory evolution dissolution neural function based on idea basic sensorimotor processes become embedded networks connections relate them successively more complex ways to allow for performance nuanced adaptive functions. noted curious link between human thought, action speech. further recognized disinhibition or...
The posterior-anterior shift in aging (PASA) is a commonly observed phenomenon functional neuroimaging studies of aging, characterized by age-related reductions occipital activity alongside increases frontal activity. In this work we have investigated the hypothesis as to whether PASA also manifested brain network measures such degree, clustering coefficient, path length and local efficiency. We performed statistical analysis upon networks derived from fMRI dataset containing data healthy...
Abstract The authors examined possible differences in left-and right-handers on bimanual reaction times to centralized visual stimuli. Eighty participants (n = 40 each group of left- and right-handers) were tested unimanual time (RT) tasks. Consistently across the 2 groups, dominant-hand RT was faster, average, than nondominant-hand RT, RTs faster RTs. However, between hands revealed a higher percentage dominant-hand-led trials left-handers, despite similar absolute groups. On basis those...
Abstract Timing variability on a repetitive tapping task was studied in subjects with unilateral cerebellar lesions. During unimanual tapping, within-hand larger when the ipsilesional hand comparison to contralesional hand. However, impaired greatly reduced tapped two hands together. The improvement during bimanual associated reduction central rather than response implementation according two-process model of Wing and Kristofferson (1973). It is proposed that (1) each half cerebellum...
Engaging in musical training has been shown to result long-term cognitive benefits. The authors examined whether basic cognitive-motor processes differ people with extensive and nonmusicians. Musicians (n = 20) nonmusicians performed a simple reaction time (RT) task under unimanual bimanual conditions. Musicians' RTs were faster overall than those of nonmusicians, who began their at an earlier age (around 7-8 years, on average) exhibited larger cost did later 12 average). conclude that...
Augmented reality (AR) has the potential to change way therapy and rehabilitation is understood administered. It can be used manipulate experience of reality, resulting in novel rehabilitative applications including but not limited augmented mirror box (AMB) manipulations. We present a conceptual framework for effective use AR therapeutic context developed around aspects belief, interactivity, predictability, decoupling. This based on previous work perception emotion manipulation derived...
Abstract Motor skill learning plays a crucial role in human functioning and is often studied using transcranial magnetic stimulation (TMS) to assess corticospinal excitability (CSE). CSE, which reflects the motor system’s responsiveness, compared across experimental conditions determine whether factor facilitates or inhibits learning. However, variability predictability may confound interpretation of CSE measures. In this study, we examined impact TMS on by comparing motor-evoked potential...
The corpus collosum is the large band of fibers that connects two cerebral hemispheres brain. Individuals who have had these tracts surgically severed by callosotomy are able to draw different spatial figures simultaneously using left and right hands, without evidence interactions in planning processes. Paradoxically, tasks (e.g., tying shoes) appear depend on between each which controlled a separate hemisphere, pose little difficulty. How can this be? In study reported here, we observed...
Mixed reality rehabilitation systems and games are demonstrating potential as innovative adjunctive therapies for health professionals in their treatment of various hand upper limb motor impairments. Unilateral deficits the arm, example, commonly experienced post stroke. Our TheraMem system provides an augmented game environment that contributes to this increasingly rich area research. We present a prototype which "fools brain" by visually amplifying users' movements — small actual lead...