Takeaki Noguchi

ORCID: 0009-0006-5781-260X
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About
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Research Areas
  • Urologic and reproductive health conditions
  • Urinary and Genital Oncology Studies
  • Prostate Cancer Diagnosis and Treatment
  • IgG4-Related and Inflammatory Diseases
  • Cancer Diagnosis and Treatment
  • Sarcoma Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Bladder and Urothelial Cancer Treatments
  • Genital Health and Disease
  • Cancer Immunotherapy and Biomarkers
  • Bone Tumor Diagnosis and Treatments
  • Urological Disorders and Treatments
  • Prostate Cancer Treatment and Research
  • Gastrointestinal disorders and treatments
  • Testicular diseases and treatments

Kanagawa Prefectural Hospital Organization
2022-2024

Kanagawa Cancer Center
2022-2024

Yokohama City University Medical Center
2024

Yokohama City University
2024

Yokohama Minami Kyosai Hospital
2023

Introduction Inflammatory myofibroblastic tumors are difficult to diagnose because of the lack specific indicators. We describe a diagnostically challenging case an inflammatory tumor primary peritoneum. Case presentation The patient was 25‐year‐old male who presented at our hospital with lower abdominal pain. Computed tomography revealed mass lesion 80 mm in diameter just above bladder. This suspected be bleeding urachus. Since malignancy could not ruled out, surgery planned. fragile...

10.1002/iju5.12701 article EN cc-by-nc-nd IJU Case Reports 2024-02-14

Introduction: This study aimed to identify immune mediators, including cytokines, chemokines, and growth factors, in the plasma for predicting treatment efficacy immune-related adverse events (irAEs) advanced urothelial carcinoma (aUC) treated with checkpoint inhibitors (ICIs). Methods: We enrolled 57 patients aUC who were anti-programmed cell death protein 1 (PD-1) antibody pembrolizumab after failure of platinum-based chemotherapy between February 2018 December 2020. Plasma levels 73...

10.3389/fphar.2023.1269935 article EN cc-by Frontiers in Pharmacology 2023-11-13

Introduction Low‐grade fibromyxoid sarcoma is an uncommon deep‐seated soft‐tissue that occurs rarely in young adults and children. Although surgical resection provides a long‐term prognosis, late local recurrence metastasis may occur. Case presentation A 44‐year‐old woman with no prior medical history presented breathing abdominal discomfort. Contrast‐enhanced computed tomography scan revealed retroperitoneal tumor protruding into the thoracic cavity pleural effusion on left side. Tumor...

10.1002/iju5.12718 article EN cc-by-nc-nd IJU Case Reports 2024-03-03

Prostate ductal adenocarcinoma, a rare histology observed in 0.4-0.8% of all prostate cancers, is treated similarly to acinar adenocarcinoma but tends have higher likelihood metastasis, recurrence, and poorer prognosis.

10.1186/s13256-024-04699-6 article EN cc-by-nc-nd Journal of Medical Case Reports 2024-08-17

症例は50代男性.右陰囊違和感を自覚し前医初診した.胚細胞腫瘍マーカーは正常値であったが右精巣腫瘍の診断で右高位精巣摘除術を施行された.組織診断では粘液産生を認める腺癌が疑われ免疫染色ではCK,CAM5.2,CEA,CA19-9,CK7,CK20陽性であった.病理結果をふまえた血液検査でCEAとCA19-9は高値を認めた.全身検索の結果,傍大動脈リンパ節の腫大を認め後腹膜リンパ節郭清施行し血清CEAは正常化した.術後4カ月後に亀頭腹側に疼痛を伴う結節が出現し血清CEAも再上昇したため陰茎全摘術を施行,病理結果は精巣腺癌の転移でありCEAは正常化した.術後9カ月後のCTで肺への転移が疑われCEA再上昇も認めたためTIP(パクリタキセル,イホマイド,シスプラチン)療法を開始した.2コース施行後のCTで肺転移は消失,血清CEAも正常化したが5カ月後の胸部CTで新たな肺転移を認めた.現在,高位精巣摘除後2年以上経過し生存している.

10.5980/jpnjurol.113.78 article JA The Japanese Journal of Urology 2022-04-20

Mucinous cystic tumor of low malignant potential (MCTLMP) is a very rare disease.The patient was 50-year-old man. Contrast-enhanced computed tomography and magnetic resonance imaging showed multiocular lesion on the top bladder. We performed surgery to remove for definitive diagnosis. Intraoperative rapid pathological diagnosis cyst wall no findings, so we combined resection peritoneum part bladder wall.Based location, immunostaining findings (CK20 CDX2 positivity; β-catenin negativity),...

10.5980/jpnjurol.114.128 article EN The Japanese Journal of Urology 2023-10-20
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