A5029867852- 3D Printing in Biomedical Research
- Synthesis and properties of polymers
- Nanofabrication and Lithography Techniques
- Membrane Separation and Gas Transport
- Graphene and Nanomaterials Applications
- Bone Tissue Engineering Materials
- Supramolecular Self-Assembly in Materials
- Fuel Cells and Related Materials
- biodegradable polymer synthesis and properties
- Polymer Surface Interaction Studies
- Click Chemistry and Applications
- Conducting polymers and applications
- Molecular Junctions and Nanostructures
- Surface Modification and Superhydrophobicity
- Diamond and Carbon-based Materials Research
- Inflammatory mediators and NSAID effects
- Genomics, phytochemicals, and oxidative stress
- Covalent Organic Framework Applications
- Immune cells in cancer
- Advanced biosensing and bioanalysis techniques
National Taiwan University
2020-2024
Marine Biomedical Research Institute of Qingdao
2020
Abstract Designing a successful biological interface for biomaterial requires the application of concepts from multiple fields, including materials science, surface nanoscience, physics, and biochemistry. With current biomaterials, such as polymers, ceramics, natural materials, original inherent properties these no longer suffice needs advanced stringent biotechnological medical applications that require controlled precision physical biochemical properties. Thus, development modifications to...
Abstract Poly( para ‐xylylene) (PPX) is a robust and biocompatible coating material that widely used in various applications, including electronics, aerospace defense materials, automotive biomaterials. In this progress report, recent developments PPX technology ranging from the advancement of physical chemistry properties structural for device integration to transformation 3D monolith materials with controls outer inner structures at micro‐ nanometer scales are highlighted. Based on...
Tissue engineering based on the combined use of isolated cells, scaffolds, and growth factors is widely used; however, manufacture cell-preloaded scaffolds faces challenges. Herein, we fabricated a multicomponent scaffold with multiple component accommodations, including bioactive molecules (BMs), such as fibroblast factor-2 (FGF-2) l-ascorbic acid 2-phosphate (A2-P), living cells human adipose-derived stem (hASCs), within one construct. We report an innovative fabrication process...
Vapor deposition of polymers is known to result in densified thin films, and recent developments have advanced these with interesting fabrication techniques a variety controlled structures other than films. With the advantages chemical modification functionalization polymers, advancements combined both physical properties vapor-deposited obtain anisotropic including layer-by-layer, gradient, hierarchical, porosity, combination above, meaning that produced are functional addressed devised...
Abstract Background Lung cancer has the highest morbidity and mortality in world novel treatment strategies are still needed. Haimufang decoction (HMF) is a patented clinical prescription of traditional Chinese medicine for lung treatment. HMF composed four herbs been applied clinically advanced patients. However, its therapeutic mechanisms unclear. This study aims to elucidate possible cancer. Methods 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide assay was evaluating...
A regulatable bioremediation capsule material was synthesized with isolated single-strain bacteria (Bacillus species, B. CMC1) and a regulator molecule (carboxymethyl cellulose, CMC) by vapor-phased encapsulation method simple steps of water sublimation poly-p-xylylene deposition in chemical vapor (CVD) process. Mechanically, the construct exhibited controllable shape dimensions, composed highly biocompatible as matrix homogeneously distributed CMC molecules. Versatility molecules at desired...
A vapor-phase process, involving the sublimation of an ice substrate/template and vapor deposition a maleimide-functionalized poly-p-xylylene, has been reported to synthesize advanced porous material, with readily clickable chemical interface properties, perform Michael-type addition maleimide functionality for conjugation thiol group. In contrast conventional poly-p-xylylenes on solid surface that forms thin film coatings, process herein additionally results in dynamic sublimating...
Conventional porous materials are mostly synthesized in solution-based methods involving solvents and initiators, the functionalization of these usually requires additional complex steps. In current study, a methyl propiolate-functionalized poly-p-xylylene material was fabricated based on unique vapor sublimation deposition process. The process used water solution ice as template with customizable shape dimensions, conventional chemical (CVD) polymerization such an formed three-dimensional,...
Biointerface Coatings for Biomaterials In article 2202286, Hsien-Yeh Chen and colleagues review biological interface coatings technologies biomaterials devices. Discussions from structural biochemical perspectives provide insights into the developments of biointerface with combinatorial complementary properties multiple disciplines size scales. Important criteria designing prospective biointerfaces are also suggested.