A5103096653- Dermatology and Skin Diseases
- Tryptophan and brain disorders
- Stress Responses and Cortisol
Northeast Agricultural University
2024-2025
Indoleamine 2, 3-dioxygenase (IDO) is a potent immunoenzyme found in dendritic cells (DCs). Research has demonstrated that Trichinella spiralis induces IDO expression the host immune response through its excretory-secretory (ES) antigens. However, role of to T. remains unclear. To examine effects ES antigens on DCs vitro , assessments were conducted using qRT-PCR, Western blotting (WB), flow cytometry, and siRNA transfer. The findings indicated antigen stimulation upregulated . Furthermore,...
Rheumatoid arthritis (RA) represents the autoimmune disorder that shows aggressive as main symptom. It is difficult to treat and can lead joint deformation function loss. At present, Trichinella spiralis (T. spiralis) antigen has attracted much attention because it plays a role in host immune regulatory mechanisms. Therefore, we selected T. recombinant protein 43 (Tsp43) bovine collagen type II (BCII)-induced mice RA model explored its therapeutic This work first verified Tsp43 could promote...