A5055431212- Genetics and Neurodevelopmental Disorders
- Neuropeptides and Animal Physiology
- Genetic Neurodegenerative Diseases
- Neurotransmitter Receptor Influence on Behavior
- Epigenetics and DNA Methylation
- Nuclear Receptors and Signaling
- Dementia and Cognitive Impairment Research
- Diet and metabolism studies
- Microtubule and mitosis dynamics
- Bipolar Disorder and Treatment
- Receptor Mechanisms and Signaling
- Nitric Oxide and Endothelin Effects
- Renin-Angiotensin System Studies
- Hypothalamic control of reproductive hormones
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Estrogen and related hormone effects
- Biochemical effects in animals
- Hormonal Regulation and Hypertension
- Neurological disorders and treatments
- Peroxisome Proliferator-Activated Receptors
- Growth Hormone and Insulin-like Growth Factors
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Neuroscience and Neuropharmacology Research
- Schizophrenia research and treatment
China Medical University
2013-2022
Sartorius (United States)
2017
First Hospital of China Medical University
2014-2016
Background: Stathmin1 (Stmn1) is a protein highly expressed during the development of central nervous system. The phosphorylation Stmn1 involves microtubule dynamics, so plays vital part in neurite outgrowth and synaptic plasticity. Previous studies reported that genetic variants influence fear anxiety as well cognitive-affective processing. However, no study on relationship between gene polymorphism cognition Chinese. Thus, this association was investigated present study. Methods: A total...
Stathmin 1 (Stmn1) is a neuronal growth-associated protein which was found to be involved in fear processing both animals and humans. Moreover, it has been demonstrated that 2 single nucleotide polymorphisms (SNPs) of the Stmn1 gene (rs182455 rs213641) significantly impacted individual anxiety responses German. However, there have no reports on correlation between SNPs Chinese. The present study thus aimed explore such correlation. A sample 567 healthy Han Chinese adults were genotyped for...
Neurotensin receptor 1 (NTR1) is a neurotensin (NT) subtype with high affinity for NT. NT and NTR1 signaling are involved in modulating the dopamine system. Individual variations system have been demonstrated to determine certain dimensions of personality, but no studies thus far investigated involvement biological determination personality. We therefore examined this link Chinese Han population.We genotyped 3 single nucleotide polymorphisms (SNPs) (rs6090453C/G, rs6011914C/G, rs2427422A/G)...
This study recruited 148 lung cancer patients and 157 healthy Chinese individuals to evaluate the personality traits of using Tridimensional Personality Questionnaire investigate associations between these rs6090453C/G rs6011914C/G polymorphisms neurotensin receptor 1 gene. The results demonstrated significant differences in total subscale scores 2 groups. Significant were found reward dependence (RD2) score genotypes harm avoidance (HA), HA1, HA2, HA4, RD2 genotypes. Thus, with have...
Previous studies have analyzed the association between nitric oxide synthase 1 adaptor protein (NOS1AP) polymorphisms and schizophrenia; however, results were inconsistent there was a lack of evidence in larger sample Chinese Han population.We decided to determine four NOS1AP single-nucleotide (i.e., rs1858232A/G, rs4531275C/T, rs4657178C/T, rs6704393C/T) schizophrenia northern population (350 patients 522 controls) using restriction fragment length polymorphism.Between group healthy group,...