About
Contact & Profiles
A5092096175
Research Areas
- Cannabis and Cannabinoid Research
- HER2/EGFR in Cancer Research
- Nitric Oxide and Endothelin Effects
- Diet, Metabolism, and Disease
- Neurotransmitter Receptor Influence on Behavior
- Pulmonary Hypertension Research and Treatments
- Computational Drug Discovery Methods
- Sulfur Compounds in Biology
- Monoclonal and Polyclonal Antibodies Research
- Pharmaceutical Practices and Patient Outcomes
- Biosimilars and Bioanalytical Methods
- Pharmaceutical studies and practices
Medical University of Białystok
2023-2025
The enhancement of the endocannabinoid tone might have a beneficial influence on hypertension. Polypharmacology proposes multi-target-directed ligands (MTDLs) as potential therapeutic agents for treatment complex diseases. In present paper, we studied JZL195, dual inhibitor two major endocannabinoid-degrading enzymes, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), in spontaneously hypertensive rats (SHR) normotensive Wistar Kyoto (WKY). Hemodynamic parameters were...
10.3390/ijms241310942
article
EN
International Journal of Molecular Sciences
2023-06-30
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