Guadalupe Pulido

ORCID: 0009-0007-3513-4251
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About
Contact & Profiles
Research Areas
  • Medicinal Plants and Neuroprotection
  • Heavy Metal Exposure and Toxicity
  • Anesthesia and Neurotoxicity Research
  • Metabolism, Diabetes, and Cancer
  • Trace Elements in Health
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Pancreatic function and diabetes
  • Regulation of Appetite and Obesity
  • Alzheimer's disease research and treatments
  • Memory and Neural Mechanisms
  • Biochemical effects in animals

Benemérita Universidad Autónoma de Puebla
2019-2022

Abstract Metabolic syndrome (MS) is a health problem that characterized by body fat accumulation, hypertension, dyslipidemia, and hyperglycemia; recently, it has been demonstrated MS also damages memory processes. The first‐line drug in the treatment of type 2 diabetes mellitus metformin, which an antihyperglycemic agent. This shown to produce neuroprotection improve However, mechanism involved this unknown. A 90‐day administration metformin improved cognitive processes rats with as...

10.1002/syn.22153 article EN Synapse 2020-03-19

Cadmium (Cd) is a heavy metal classified as carcinogen whose exposure could affect the function of central nervous system. Studies suggest that Cd modifies neuronal morphology in hippocampus and affects cognitive tasks. The oxidative stress pathway proposed mechanism toxicity. However, this not precise yet. This study aimed to evaluate effect administration on markers male rat's hippocampus. Male Wistar rats were divided into (1) control (drinking water) (2) treatment with (32.5 ppm cadmium...

10.1002/syn.22242 article EN Synapse 2022-06-16

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by dementia and the aggregation of amyloid beta peptide (Aβ). Aβ25–35 most neurotoxic sequence, whose mechanism associated with neuronal death in Cornu Ammonis 1 (CA1) region hippocampus (Hp) cognitive damage. Likewise, there are mechanisms survival regulated heat shock proteins (HSPs). Studies indicate that pharmacological treatment flavonoids reduces prevalence AD, particularly epicatechin (EC), which shows better...

10.3390/antiox8050113 article EN cc-by Antioxidants 2019-04-30
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