A5090791949- Gut microbiota and health
- Inflammatory Bowel Disease
- Immune Cell Function and Interaction
- Eosinophilic Esophagitis
- T-cell and B-cell Immunology
- Reproductive System and Pregnancy
- Essential Oils and Antimicrobial Activity
- Barrier Structure and Function Studies
- S100 Proteins and Annexins
- IL-33, ST2, and ILC Pathways
- Traditional Chinese Medicine Analysis
- Aquaculture disease management and microbiota
- Pharmacological Effects of Natural Compounds
- Cancer-related molecular mechanisms research
- Inflammation biomarkers and pathways
- Mycobacterium research and diagnosis
Gansu Agricultural University
2022-2025
Zhongshan Hospital of Xiamen University
2023
Abstract Background Cellular immunity mechanisms play a crucial role in regulating anti-parasite immunity. ICOS is one of the core factors multitype T cell subsets involved regulation immune homeostasis. The aim this experiment was to investigate distribution patterns + cells small intestine sheep and determine impact Moniezia benedeni ( M. ) infection on these cells. Methods In study, pET-28a-ICOS recombinant plasmid constructed, protein obtained through induced expression BL21 (DE3)...
The intestinal flora maintained by the immune system plays an important role in healthy colon. However, of ILC3s-TD IgA-colonic mucosal axis ulcerative colitis (UC) and whether it could become innovative pathway for treatment UC is unknown. Yujin Powder a classic prescription dampness-heat type intestine disease traditional Chinese medicine has therapeutic effects on UC. Hence, present study aimed to investigate regulatory mechanism alcoholic extracts (YJP-A) via axis. mouse model was...
The intestinal mucosal immune system, renowned for its precise and sensitive regulation, can provide comprehensive effective protection the body, among which ileum is a critical induction site regulating homeostasis. Moniezia benedeni parasitizes small intestine of sheep cause serious pathological damage or even death to host when infection severe. In this study, 5 infected with were selected as group, uninfected control group. ileal transcriptome profile characteristics analyzed based on...
Crohn's disease (CD) is a chronic inflammatory disease, and its incidence gradually increasing. Thus, the use of simple convenient examination method to detect CD in natural population as early possible crucial. This study aimed at using colloidal gold semiquantitative assay fecal calprotectin (FCP) determine whether it helpful screening or diagnosing CD.Using prospectively maintained database, 59 patients with were analyzed FCP measurement. Subsequently, 76 89 healthy individuals assigned...
Here, we aimed to optimize the ethanol extraction technology for Yujin powder (YJP) and evaluate its safety. The ultrasonic-assisted reflux method refluxing was used extract YJP. parameters were optimized through a combination of single-factor response surface methodology (RSM). comprehensive Y value score calculated using content 13 active ingredients in YJP ethanolic extracts (YEEs) yield dry as measuring criteria. RSM with Box-Behnken design three factors levels adopted Finally, acute...