A5026930587- Nanoparticle-Based Drug Delivery
- Inorganic Chemistry and Materials
- Graphene and Nanomaterials Applications
- Iron oxide chemistry and applications
- Characterization and Applications of Magnetic Nanoparticles
- Advanced Photocatalysis Techniques
- Retinoids in leukemia and cellular processes
- Microtubule and mitosis dynamics
- Synthesis and Reactivity of Heterocycles
- Chemotherapy-induced organ toxicity mitigation
- Layered Double Hydroxides Synthesis and Applications
University of Edinburgh
2019-2025
Bioengineering (Switzerland)
2019
Ege University
2017
This work suggests that, in the presence of a magnetic field, size and magnetization ultrasmall superparamagnetic Fe 3 O 4 nanoparticles play dominant roles tumor penetration.
Cisplatin (CDDP) is one of the most commonly used chemotherapeutic agents for solid tumors and hematologic malignancy. However, its therapeutic outcomes have remained unsatisfactory due to severe side effects, a short elimination half-life, emergence drug resistance, induction metastasis. Combination with other has been proposed as strategy address drawbacks CDDP-based therapy. Therefore, this study aimed boost antitumor efficacy cisplatin PI3K/mTOR dual inhibitor, dactolisib (BEZ), via...
Amaç: Serin/treonin protein kinaz olan aurora kinazlar, hücrelerin uygun mitotik ilerlemeden sorumlu önemli moleküllerdir.Kanser hücrelerinde anormal olarak ifade edildikleri bilinmekte ve bu nedenle bir terapötik hedefler görülmektedir.CCT137690, yüksek oranda seçici özellik gösteren sentetik inhibitörüdür.Bu çalışmada CCT137690'un KU812 hücreleri (insan kronik miyeloid lösemi-KML) üzerinde apoptotik antiproliferatif etkilerinin belirlenmesi