A5059236430- RNA and protein synthesis mechanisms
- Urban Planning and Valuation
- Phase Equilibria and Thermodynamics
- Historical and Environmental Studies
- Ubiquitin and proteasome pathways
- Advanced Thermodynamics and Statistical Mechanics
- Fungal and yeast genetics research
- CRISPR and Genetic Engineering
- Biochemical Analysis and Sensing Techniques
- Thermodynamic properties of mixtures
- Diverse academic and cultural studies
- Endoplasmic Reticulum Stress and Disease
University of Sannio
2023-2025
Photolyases repair UV damage to DNA by using absorbed blue light. Within the photolyase/cryptochrome superfamily (PCSf), a major subgroup consists of prokaryotic (6-4) photolyases. These enzymes rely on flavin adenine dinucleotide (FAD) as catalytic cofactor, besides an ancillary antenna chromophore, and [4Fe-4S] cluster with yet unknown function. For 6-4 photolyase Caulobacter crescentus, we investigated structural changes associated its different redox states damage-free crystallography...
Protein quality control (PQC) mechanisms are essential for degradation of misfolded or dysfunctional proteins. An part protein homeostasis is recognition defective proteins by PQC components and their elimination the ubiquitin–proteasome system, often concentrating on termini as indicators integrity. Changes in amino acid composition C-terminal ends arise through disintegration, alternative splicing, during translation step synthesis from premature termination translational stop-codon...