A5083139841- Quinazolinone synthesis and applications
- Machine Learning in Bioinformatics
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Mycobacterium research and diagnosis
- Genomics and Phylogenetic Studies
Rice University
2024
University of Ghana
2022
The advent of long-read sequencing microbiomes necessitates the development new taxonomic profilers tailored to shotgun metagenomic datasets. Here, we introduce Lemur and Magnet, a pair tools optimized for lightweight accurate profiling is marker-gene-based method that leverages an EM algorithm reduce false positive calls while preserving true positives; Magnet whole-genome read mapping based provides detailed presence absence bacterial genomes. We demonstrate can run in minutes hours on...
Buruli ulcer (BU), a severe skin disease is caused by Mycobacterium ulcerans. There are concerns of therapeutic inefficacy existing drugs coupled with chemoresistance. Databases have been shown to augment data mining and integrative systems pharmacology approaches towards the search for novel moieties. So far, there no known integrated database solely dedicated BU drug discovery. In this work, (BuDb) “one-stop-shop” knowledgebase supporting It contains both manually verified literature...