A5114778236- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Pharmacological Receptor Mechanisms and Effects
- Inflammatory mediators and NSAID effects
- Medical Imaging Techniques and Applications
- Psoriasis: Treatment and Pathogenesis
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Face and Expression Recognition
- Sparse and Compressive Sensing Techniques
- Machine Learning in Materials Science
- Gas Sensing Nanomaterials and Sensors
- Advanced Graph Neural Networks
- Medical Image Segmentation Techniques
- Probabilistic and Robust Engineering Design
- Rough Sets and Fuzzy Logic
- Sports Analytics and Performance
- Data Visualization and Analytics
- Human-Automation Interaction and Safety
- Amino Acid Enzymes and Metabolism
- Digital Radiography and Breast Imaging
- Lung Cancer Diagnosis and Treatment
- NF-κB Signaling Pathways
- Cultural and Religious Practices in Indonesia
- Ergonomics and Musculoskeletal Disorders
Fudan University
2022-2024
Northeast Normal University
2024
Tsinghua University
2024
Minhang District Central Hospital
2022
New York University
2020
University of Science and Technology of China
2017-2019
University of California, Berkeley
2016
Duke University
2010-2014
Advanced Imaging Research (United States)
2013
Purpose: For nonlinear iterative image reconstructions (IR), the computed tomography (CT) noise and resolution properties can depend on specific imaging conditions, such as lesion contrast level. Therefore, it is imperative to develop a reliable method measure under clinically relevant conditions. This study aimed robust methodology three-dimensional CT conditions provide guidelines achieve desirable levels of accuracy precision. Methods: The was developed based previously reported quality...
Abstract To explore highly selective targeting molecules of colorectal cancer (CRC) is a challenge. We previously identified twelve-amino acid peptide (LPKTVSSDMSLN, namely P-LPK) by phage display technique which may specifically binds to CRC cells. Here we show that P-LPK selectively bind panel human cell lines and tissues. In vivo, Gallium-68 ( 68 Ga) labeled exhibits accumulation at tumor sites. Then, designed peptide-conjugated drug comprising camptothecin (CPT) (namely P-LPK-CPT), found...
Guided by the mode of action
The quantification of lung nodule volume from CT images provides valuable information for cancer diagnosis and staging. However, the usefulness depends on its precision. Direct assessment precision involves multiple steps can become intractable a multiplicity protocols. To assess efficiently, we developed prediction model, named estimability index (<i>e</i>'). <i>e</i>' based characteristics image noise resolution, being quantified, segmentation software. It was further calibrated against...
Abstract This article aims to illustrate that one fundamental reason why the Chinese civilization has remained strong and resilient for over five thousand years it even become stronger in recent times, despite facing numerous challenges. is due cultural beliefs embedded traditional culture. Through analysis, synthesis, comparison, this demonstrate that, unlike Western religious beliefs, faith embodied culture a typical humanistic faith, including people’s nature, ancestors, “Tian Di” (Heaven...
This study aimed to extend Fourier-based imaging metrics for the modeling of quantitative performance. Breast tomosynthesis was used as a platform investigating acquisition and processing parameters (e.g., angle dose) that can significantly affect 3D signal noise, consequently The detectability index computed using modulation transfer function noise-power spectrum combined with Fourier description task. Three tasks were considered: detection, area estimation (in coronal slice), volume 4 mm...
Opioid receptors are members of the group G protein-couple receptors, which have been proven to be effective targets for treating severe pain. The interactions between opioid and corresponding ligands receptor's activation by different agonists among most important fields in research. In this study, with compound M1, an active metabolite tramadol, as clue compound, several aminomethyl tetrahydronaphthalenes were designed, synthesized assayed upon receptors. With resultant compounds...
Current lung nodule size assessment methods typically rely on one-dimensional estimation of lesions. While new 3D volume techniques using MSCT scan data have enabled improved lesion size, the effect acquisition and reconstruction parameters accuracy precision such has not been adequately investigated. To characterize dependencies, we scanned an anthropomorphic thoracic phantom containing synthetic nodules with different protocols, including various parameters. We also repeatedly same...
To fabricate a virtual shape into the real world, physical strength of is an important consideration. We introduce framework to consider both and complexity 3D frame structures. The key stress-oriented analysis semi-continuous condition in representation that can strengthen simplify structure at same time. formulate novel optimization solved by elegant method. demonstrate our approach with applications such as topology simplification structural strengthening.