Marcella Sozzoni
A5025531229- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Chromosomal and Genetic Variations
- Genetics, Bioinformatics, and Biomedical Research
- Genetic and Environmental Crop Studies
- Biofuel production and bioconversion
- Environmental DNA in Biodiversity Studies
University of Florence
2023-2024
University of Milan
2022-2023
Insights into the evolution of non-model organisms are limited by lack reference genomes high accuracy, completeness, and contiguity. Here, we present a chromosome-level, karyotype-validated genome pangenome for barn swallow (Hirundo rustica). We complement these resources with reference-free multialignment other bird most comprehensive catalog genetic markers swallow. identify potentially conserved accelerated genes using estimate genome-wide linkage disequilibrium catalog. use to infer...
Improvements in genome sequencing and assembly are enabling high-quality reference genomes for all species. However, the process is still laborious, computationally technically demanding, lacks standards reproducibility, not readily scalable. Here we present latest Vertebrate Genomes Project pipeline demonstrate that it delivers at scale across a set of vertebrate species arising over last ~500 million years. The versatile combines PacBio HiFi long-reads Hi-C-based haplotype phasing new...
Amidst the current biodiversity crisis, availability of genomic resources for declining species can provide important insights into factors driving population decline. In early 1990s, black-legged kittiwake (Rissa tridactyla), a pelagic gull widely distributed across arctic, subarctic, and temperate zones, suffered steep decline following an abrupt warming sea surface temperature its distribution range is currently listed as Vulnerable by International Union Conservation Nature. Kittiwakes...
Abstract Insights into the evolution of non-model organisms are often limited by lack reference genomes. As part Vertebrate Genomes Project, we present a new genome and pangenome produced with High-Fidelity long reads for barn swallow Hirundo rustica . We then generated reference-free multialignment other bird genomes to identify genes under selection. Conservation analyses pointed at enriched transcriptional regulation neurodevelopment. The most conserved gene is CAMK2N2 , potential role in...