A5071374887- Mesenchymal stem cell research
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Musculoskeletal pain and rehabilitation
- Periodontal Regeneration and Treatments
- Rheumatoid Arthritis Research and Therapies
- Anesthesia and Pain Management
- Myofascial pain diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Biomarkers in Disease Mechanisms
- Systemic Lupus Erythematosus Research
Royan Institute
2022-2023
Academic Center for Education, Culture and Research
2022-2023
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease of unknown cause. The interaction immune system cells and the secretion inflammatory cytokines with synovial leads to severe inflammation in affected joints. Currently, medications, including non-steroidal anti-inflammatory drugs, glucocorticoids, more recently, disease-modifying anti-rheumatic are used reduce inflammation. However, long-term use these drugs causes adverse effects or resistance considerable number RA...
The collagen-induced arthritis (CIA) model is the most commonly studied autoimmune of rheumatoid (RA). In this study, we investigated usefulness collagen type II emulsified in Freund's incomplete adjuvant (CII/IFA) as a suitable method for establishing RA Lewis rats. aim present study was to straightforward and effective inducing CIA
Animal models provide a deeper understanding about various complications and better demonstrate the effect of therapeutic approaches. One issues in low back pain (LBP) model is invasiveness procedure it does not mimic actual disease conditions humans. The purpose present study was to compare ultrasound-guided (US-guided) percutaneous approach with open-surgery method tumor necrosis factor-alpha (TNF-α)-induced disc degeneration for first time showcase advantages this recently developed,...