A5072116881- DNA and Nucleic Acid Chemistry
- Advanced Fluorescence Microscopy Techniques
- Advanced biosensing and bioanalysis techniques
- Ion-surface interactions and analysis
- Nanopore and Nanochannel Transport Studies
- Carbon Nanotubes in Composites
Technische Universität Dresden
2023
Raman Research Institute
2020
Single-molecule FRET (smFRET) has become a versatile tool for probing the structure and functional dynamics of biomolecular systems, is extensively used to address questions ranging from folding drug discovery. Confocal smFRET measurements are amongst widely assays typically performed in single-well format. Thus, sampling many experimental parameters laborious time consuming. To this challenge, we extend here capabilities confocal beyond by integrating multiwell plate functionality allow...
We show detailed understanding of enzyme dependent structural changes in supercoiled DNA along with a quantitative analysis its branches using nanopores.