A5097956713- Metabolomics and Mass Spectrometry Studies
- Mass Spectrometry Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Analytical chemistry methods development
- Isotope Analysis in Ecology
- Biosensors and Analytical Detection
- Analytical Chemistry and Chromatography
University of Vienna
2024
Medical University of Vienna
2024
State-of-the-art quantitative metabolomics relies on isotope dilution using internal standards (IS) derived from fully
We introduce TRAM, a triple acquisition strategy on high-speed, time-of-flight mass spectrometry for merging non-targeted and targeted metabolomics into one run. TRAM stands “quasi-simultaneous” of (1) full scan MS1, (2) top 30 data-dependent MS2 (DDA), (3) scheduled multiple reaction monitoring (MRM) within measurement cycles ~ 1 second. combines the selectivity sensitivity state-of-the-art MRM-based methods with scope analysis enabled by high-resolution spectrometry. In this work, we...
We introduce TRAM, a triple acquisition strategy on high-speed quadrupole time-of-flight mass spectrometer for merging non-targeted and targeted metabolomics into one run. TRAM stands "quasi-simultaneous" of (1) full scan MS1, (2) top 30 data-dependent MS2 (DDA), (3) scheduled multiple reaction monitoring (MRM) within measurement cycles ∼1 s. combines the selectivity sensitivity state-of-the-art MRM-based methods with scope analysis enabled by high-resolution spectrometry.