A5100629702- Advanced biosensing and bioanalysis techniques
- Endoplasmic Reticulum Stress and Disease
- Biosensors and Analytical Detection
- Extracellular vesicles in disease
- Bacterial biofilms and quorum sensing
- CRISPR and Genetic Engineering
- Medicinal Plants and Bioactive Compounds
- Alzheimer's disease research and treatments
- Neonatal Respiratory Health Research
- Advanced Biosensing Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Selenium in Biological Systems
- Antibiotic Resistance in Bacteria
- Mycotoxins in Agriculture and Food
- Gold and Silver Nanoparticles Synthesis and Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Bioactive natural compounds
- Tryptophan and brain disorders
- Inflammasome and immune disorders
- Mitochondrial Function and Pathology
- Vibrio bacteria research studies
- Wound Healing and Treatments
- Diet and metabolism studies
- Genetics, Aging, and Longevity in Model Organisms
- Supramolecular Self-Assembly in Materials
Sichuan University
2022-2024
Zhejiang Chinese Medical University
2020-2024
Research Center for Eco-Environmental Sciences
2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Chengdu University
2023
Huazhong Agricultural University
2022
Daping Hospital
2018
Army Medical University
2018
Abstract Supramolecular hydrogels derived from nucleosides have been gaining significant attention in the biomedical field due to their unique properties and excellent biocompatibility. However, a major challenge this is that there no model for predicting whether nucleoside derivative will form hydrogel. Here, we successfully develop machine learning predict hydrogel-forming ability of derivatives. The optimal with 71% (95% Confidence Interval, 0.69−0.73) accuracy established based on...
Bacterial biofilms (BFs) are widely present in nature, and more than 99% of bacteria can form BF, which is an important factor leading to persistent infection refractory wound repeated infection. The formation BF a dynamic cyclic process involving various physical, chemical biological processes, mainly including bacterial attachment, maturation, diffusion. resistant antibiotics disinfectants, resilient environmental changes, presents many challenges treatment. This article reviews the basic...
Aflatoxin B1 (AFB1) exists widely in feed and food with severe hazards, posing a serious threat to human animal health. Epigallocatechin gallate (EGCG) glutathione (GSH) have been reported as having anti-oxidative other functions. The present study aimed investigate the detoxification effect of EGCG GSH alone or combination on AFB1 exposure ducklings. Fifty one-day-old male ducklings were randomly assigned into five experimental groups (n = 10): 1. Control (CTR); 2. 0.3 mg/kg BW (AFB1); 3. +...
At present, the multiple drug resistance of Acinetobacter baumannii outbreaks worldwide and has intensified trend, especially in intensive care unit burn ward. Generic resistant is known as 21st century gram-negative bacterium "MRSA", "Superbugs". In recent years, researches have shown that this associated with pathogenic bacteria to form biofilms. paper, status infection, biofilm formation, mechanism prevention years were summarized.
Inflammation is generally considered as a pathological process, and the occurrence of multi-organ inflammatory diseases usually accompanied by an response. Persistent inflammation can eventually lead to organ dysfunction. In recent years, study mesenchymal stem cell-derived exosomes has found its unique anti-inflammatory effect, which provides new idea for treatment diseases. This article reviews effect cell on
To investigate the regulatory effect of iridoid glycoside radix scrophulariae (IGRS) on endoplasmic reticulum stress induced by oxygen-glucose deprivation and reperfusion in vitro model.Rat pheochromocytoma PC12 cells were pretreated with IGRS (50, 100, 200 μg/mL) for 24h, model deprivation/reoxygenation (OGD/R) was applied. The cell viability determined MTT lactate dehydrogenase (LDH) assay. apoptotic rate detected flow cytometry. expression B-cell lymphoma-2 (Bcl-2), Bcl-2 related X...
Objective To study of promotion effect adipose derived stem cells-exosomes (ADSC-Exo) on fibroblast proliferation from granulation tissues. Methods Waste tissue after operation was collected Third Affiliated Hospital Inner Mongolia Medical University, ADSC-Exo were isolated by using ultrafiltration method, morphology observed Nanosight and electron microscope, expression proteins detected Western Blotting, particle size concentration measured analyzer. Granulation burn wounds...
Formyl peptide receptor 2-lipoxin (FPR2/ALX) and its agonists are well-defined mechanisms in antiinflammatory pro-resolving response, neutrophils actively participate inflammation. However, FPR2/ALX expression the effects of agonist autophagy under inflammatory circumstances not fully understood. In this study, flow cytometric analysis real-time PCR were used to detect protein mRNA healthy volunteers septic patients. The BML-111 alone or with pro-inflammatory stimulant assessed by Western...
Objective To discuss the expression of calponin in burn wound healing process diabetic rats and its effect on proliferation apoptosis fibroblasts. Methods Sixty-four Wistar male were selected divided into experimental group control according to random number table method, with 32 each group. Rats given intraperitoneal injections streptozotoci by 60 mg/kg create animal model. 0.9% sodium chloride solution 1.0 mL. Deep partial-thickness scald models (hereinafter referred as burns)...