Ali F. Almutairy

ORCID: 0009-0007-7954-4893
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About
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Research Areas
  • Molecular Biology Techniques and Applications
  • Cancer-related Molecular Pathways
  • Phytochemicals and Antioxidant Activities
  • Cancer Genomics and Diagnostics
  • Bone and Dental Protein Studies
  • Photodynamic Therapy Research Studies
  • Tryptophan and brain disorders
  • Urinary Bladder and Prostate Research
  • Multiple Myeloma Research and Treatments
  • Pediatric Urology and Nephrology Studies
  • Gene expression and cancer classification
  • Ubiquitin and proteasome pathways
  • Agricultural Practices and Plant Genetics
  • Head and Neck Cancer Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Antioxidant Activity and Oxidative Stress
  • Tea Polyphenols and Effects
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Nuclear Structure and Function
  • Skin Protection and Aging
  • Stress Responses and Cortisol
  • Ginger and Zingiberaceae research
  • Medicinal Plant Research
  • Chemotherapy-induced organ toxicity mitigation
  • Nanoplatforms for cancer theranostics

Qassim University
2023-2025

AutoNation (United States)
2019-2024

Nova Southeastern University
2019-2024

South University
2019

5-Fluorouracil (5-FU) is widely used in chemotherapy but poses serious risks of cardiotoxicity, which can significantly affect treatment outcomes. Identifying interventions that prevent these adverse effects without undermining anticancer efficacy crucial. This study investigates the Thymoquinone (TQ) and Hesperidin (HESP) preventing cardiotoxicity induced by 5-FU Wistar rats elucidates molecular interactions through docking studies. We employed an experimental design involving multiple...

10.3390/toxics12090688 article EN cc-by Toxics 2024-09-23

Background: The research is aimed at exploring the potential of marigold petal tea (MPT), rich in polyphenol contents, against oxidative stress and obesity a rat model following high‐fat‐sugar diet (HFSD). Methods: MPT was prepared through customary method decoction subjected to analysis for its composition using reversed‐phase high‐performance liquid chromatography (RP‐HPLC). Two specific doses MPT, namely, 250 500 mg/kg body weight (BW), were chosen study—referred as MPT‐250 MPT‐500,...

10.1155/2024/3833521 article EN cc-by Cardiovascular Therapeutics 2024-01-01

Human body cells are stem cell (SC) derivatives originating from bone marrow. Their special characteristics include their capacity to support the formation and self-repair of cells. Cancer multiply uncontrollably invade healthy tissues, making transplants a viable option for cancer patients undergoing high-dose chemotherapy (HDC). When is used at very high doses eradicate all aggressive tumors, blood-forming leukocytes either completely or partially destroyed. Autologous transplantation...

10.3390/cells12242855 article EN cc-by Cells 2023-12-18

Veterans of the 1991 Gulf War were potentially exposed to a mixture stress, chemicals and radiation that may have contributed persistent symptoms Illness (GWI). The genotoxic effects some these exposures are mediated by DNA nucleotide excision repair (NER) pathway. We hypothesized individuals with relatively low capacity would suffer greater damage from cumulative exposures, which persist, causing ongoing problems. Blood samples obtained symptomatic veterans age-matched controls. unscheduled...

10.1093/milmed/usz177 article EN cc-by Military Medicine 2019-07-23

<title>Abstract</title> This paper presents a comprehensive analysis of the phytochemical composition, quality parameters followed by antimicrobial and antidiabetic activity <italic>Abelmoschus esculentus</italic> (okra) plant material. The study involved macroscopic examination material for visual characteristics, screening various chemical constituents. presence flavonoids, amino acids, saponins, tannins, terpenoids, reducing sugars, triterpenes, lipids was detected, while glycosides,...

10.21203/rs.3.rs-4797363/v1 preprint EN Research Square (Research Square) 2024-09-13

Breast cancer (BC) is the most common affecting women in United States. Ductal carcinoma

10.1101/2024.02.13.580215 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-16

Abstract Background and Objectives: In 2021 breast cancer (BC) was the most common affecting women second deadliest in U.S. Ductal Carcinoma Situ (DCIS) is earliest identifiable pre-invasive lesion. Approximately 20-25% of diagnosed cases are ductal carcinoma situ (DCIS). Estimates show that 14 to 50% DCIS progress invasive cancer. We used a novel tissue-engineering system established Latimer laboratory generate model systems representative different molecular histological subtypes all...

10.1158/1538-7445.evodyn22-a033 article EN Cancer Research 2022-05-15
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