A5075772892- Molecular Biology Techniques and Applications
- MicroRNA in disease regulation
- Nerve injury and regeneration
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- Assistive Technology in Communication and Mobility
- Microplastics and Plastic Pollution
- Receptor Mechanisms and Signaling
- Cancer-related gene regulation
- Language Development and Disorders
- Muscle and Compartmental Disorders
- Poisoning and overdose treatments
- Wnt/β-catenin signaling in development and cancer
- Pain Mechanisms and Treatments
- Axon Guidance and Neuronal Signaling
- Food Security and Health in Diverse Populations
- Mercury impact and mitigation studies
- NF-κB Signaling Pathways
- Stress Responses and Cortisol
- Pharmacological Effects and Assays
- Signaling Pathways in Disease
- Heavy Metal Exposure and Toxicity
- Anesthesia and Neurotoxicity Research
- Milk Quality and Mastitis in Dairy Cows
- Botulinum Toxin and Related Neurological Disorders
Washington University in St. Louis
2025
University of Arizona
2023-2024
Google (United States)
2023
Research Institute for Farm Animal Biology (FBN)
2015-2017
Leibniz Association
2015
University of Rostock
2012
Forschungszentrum Jülich
2012
Centre National de la Recherche Scientifique
1994
Hospices Civils de Lyon
1991
ABSTRACT Introduction/Aims The function of the sterile alpha and toll/interleukin receptor motif‐containing protein 1 (SARM1) in neuropathic pain development has not yet been established. This a central role regulating axon degeneration its depletion delays this process. study aims to demonstrate effects SARM1 deletion on pain. Methods Thirty‐two wild‐type (WT) or knockout (KO) rats underwent spared nerve injury (SNI) sham surgery. Mechanical allodynia was assessed by electronic Von Frey...
Postpartum Dysgalactia Syndrome (PDS) represents a considerable health problem of postpartum sows, primarily indicated by mastitis and lactation failure. The poorly understood etiology this multifactorial disease necessitates the use porcine mammary epithelial cell (PMEC) model to identify how what extent molecular pathogen defense mechanisms prevent bacterial infections at first cellular barrier gland. PMEC were isolated from three lactating sows challenged with heat-inactivated potential...
Abstract Glycogen synthase kinase‐3beta is a multifunctional key regulator enzyme in neural developmental processes and main component of the canonical Wnt signaling pathway. It already known that Wnt‐driven differentiation progenitor cells accompanied by an increase apoptosis at which pro‐apoptotic function GSK‐3beta still discussed. The aim present study was to investigate whether phosphorylation level serine 9 primary regulatory mechanism differentiation‐induced apoptosis. Differentiating...
The primary purpose of this study was to examine the effect sentence length on speech rate and its characteristics, articulation rate, pauses in children with neurodevelopmental disorders.
We comprehensively characterized the effects of a unique natural gain-of-function mutation in glucocorticoid receptor (GR), GR Ala610Val , domestic pigs to expand current knowledge phenotypic consequences hypersensitivity. Cortisol levels were consistently reduced one-week-old piglets, at weaning and peripubertal age, probably due adrenal capacity produce glucocorticoids (GC), which was indicated by an adrenocortical thinning carriers. Adrenocorticotrophic hormone (ACTH) significantly...
Coliform mastitis is a symptom of postpartum dysgalactia syndrome (PDS), multifactorial infectious disease sows. Our previous study showed gene expression profile change after bacterial challenge porcine mammary epithelial cells (PMECs). These mRNA changes may be regulated through microRNAs (miRNAs) which play critical roles in biological processes. Therefore, miRNA was investigated PMECs. PMECs were isolated from three lactating sows and challenged with heat-inactivated potential...
The beta-2 adrenergic receptor (beta-2 AR) modulates metabolic processes in skeletal muscle, liver, and adipose tissue response to catecholamine stimulation.We showed previously that expression of the porcine AR gene (ADRB2) is affected by cis-regulatory polymorphisms.These are most likely responsible for association ADRB2 with economically relevant muscle-related traits pigs.The present study focused on characterization promoter elements involved basal transcriptional regulation different...
Student-run free clinics (SRFC) play an important role in filling gaps the healthcare system by providing accessible, cost-free care to underserved populations. Continuity of (CoC) can improve patient outcomes, but challenges such as inconsistent volunteer participation and follow-up make CoC difficult implement SRFCs. The authors acknowledge deficiencies existing literature guiding SRFCs highlight a systematic model address barriers CoC. This article proposes structured for SRFCs,...