A5069716190- Occupational and environmental lung diseases
- Head and Neck Cancer Studies
- Sinusitis and nasal conditions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Occupational exposure and asthma
- Head and Neck Surgical Oncology
- Health, Environment, Cognitive Aging
- Carcinogens and Genotoxicity Assessment
- Air Quality and Health Impacts
- Acute Lymphoblastic Leukemia research
- Delphi Technique in Research
- Inhalation and Respiratory Drug Delivery
- Climate Change and Health Impacts
- Noise Effects and Management
Danish Ramazzini Center
2017-2024
Aarhus University Hospital
2016-2024
Aarhus University
2016-2024
Background Respirable crystalline silica is a well-known cause of silicosis but may also be associated with other types interstitial lung disease. We examined the associations between occupational exposure to respirable and risk idiopathic pneumonias, pulmonary sarcoidosis silicosis. Methods The total Danish working population was followed 1977–2015. Annual individual estimated using quantitative job matrix. Cases were identified in National Patient Register. conducted adjusted analyses...
Background: Styrene is an important industrial chemical that the general population exposed to at low levels. Previous research has suggested increased occurrence of leukemia and lymphoma among reinforced plastics workers high levels styrene. Methods: We followed 73,036 456 small- medium-sized Danish companies from 1968 2011 investigated exposure-response relation between cumulative styrene exposure incidence lymphohematopoietic malignancies. modeled employment history, survey data,...
Background Organic dust is associated with hypersensitivity pneumonitis, and associations other types of interstitial lung disease (ILD) have been suggested. We examined the association between occupational organic exposure pneumonitis ILDs in a cohort study. Methods The study population included all residents Denmark born 1956 or later at least 1 year gainful employment since 1976. Incident cases were identified Danish National Patient Register 1994–2015. Job matrices used to assign...
Abstract Objective Within the scope of Exposome Project for Health and Occupational Research on applying exposome concept to working life health, we aimed provide a broad overview status knowledge occupational exposures associated health effects across multiple noncommunicable diseases (NCDs) help inform research priorities. Methods We conducted narrative review risk factors that can be considered have “consistent evidence an association,” or where there is “limited/inadequate association” 6...
The association between asbestos exposure and asbestosis in high-exposed industrial cohorts is well-known, but there a lack of knowledge about the exposure-response relationship for general working population setting. We examined occupational asbestos-exposed workers Danish population.
Background Sinonasal adenocarcinoma is a rare disease expected to have causes and potential for strong risk factors as reflected by the association with occupational wood dust exposure. High level styrene exposure suspected carcinogen, this study examines exposure–response relation between exposure, sinonasal other subtypes. Methods We followed 73 092 styrene-exposed workers from 1968 2011 identified cancers in Danish Cancer Registry. modelled cumulative estimated incidence rates age, sex...
Exposure to industrial solvents has been associated with encephalopathy. Styrene is a neurotoxic solvent, and we investigated the long-term risk of encephalopathy unspecified dementia following styrene exposure. We followed 72,465 workers in reinforced plastics industry Denmark (1977-2011) identified incident cases (n = 228) 565) national registers. Individual exposure levels were modeled from information on occupation, measurements work place levels, product, process, years employment....
In this review, we discuss a new definition and treatment options of allergic alveolitis (AA). AA is an immune-mediated interstitial lung disease triggered by inhaled antigens, it defined as non-fibrotic (inflammatory) and/or fibrotic, diagnosis relies on multidisciplinary approach using clinical, radiological sometimes histological assessments. Treatment involves early antigen elimination may include corticosteroids or other immunosuppressants. Prognosis varies from reversible inflammation...
<h3>Background</h3> Styrene is an organic solvent and a well-documented neurotoxin with effects on reaction time, colour vision, hearing thresholds. Mixed exposure has been associated encephalopathy. We investigated the long-term risk of encephalopathy other non-vascular dementia in styrene exposed reinforced plastics workers. <h3>Methods</h3> followed 77,271 workers 456 Danish companies 1968–2011 response relation between cumulated hospitalisation-defined cases (n = 258), unspecified 689)...
<h3>Introduction</h3> Occupational exposure to respirable crystalline silica is a well-known cause of silicosis, but studies have indicated that also associated with increased risk other types interstitial lung disease (ILD). Our objective was examine the different ILD following occupational exposure. <h3>Material and Methods</h3> The study population includes total Danish working 5,478,664 workers, followed 1979–2015. Annual individual estimated using quantitative job matrix. Cases were...
<h3>Objective</h3> We recently suggested an increased risk of sinonasal cancer following occupational styrene exposure. The objective the current study is to explore this finding further by including information on quantitative measures exposure and histological subcategories. <h3>Methods</h3> followed 73 092 workers employed in 456 small medium sized Danish reinforced plastics companies from 1968 2011. Incident cases were identified linkage with national Cancer Registry. modelled cumulative...
<h3>Introduction</h3> Occupational exposure to wood dust is associated with increased risk of adenocarcinoma and probably also squamous cell sinonasal cancer. There is, however, still limited knowledge about the exposure-response relation possible threshold levels. <h3>Objectives</h3> To analyze between quantitative measures <h3>Methods</h3> A cohort study was conducted entire Danish working population 1979–2015 (n=5,421,248) annual information on occupation since 1977. An inception workers...
<h3>Introduction</h3> Occupational dust exposure is associated with interstitial lung disease and chronic obstructive pulmonary disease, but little known about the association more discrete changes detected by scans. <h3>Objectives</h3> To 1) analyze relation between occupational levels HRCT (high-resolution computed tomography) signs of 2) map prevalence these in Danish workforce. <h3>Methods</h3> We are carrying out a cross-sectional study 25,000 adults who underwent scans lungs 2011–2019...