A5101436253- Asymmetric Synthesis and Catalysis
- Axial and Atropisomeric Chirality Synthesis
- Synthesis and Catalytic Reactions
- Groundwater and Isotope Geochemistry
- Catalytic C–H Functionalization Methods
- Geology and Paleoclimatology Research
- Hydrocarbon exploration and reservoir analysis
- Sulfur-Based Synthesis Techniques
- Migration, Health and Trauma
- Oxidative Organic Chemistry Reactions
- Migration and Labor Dynamics
- Organic Chemistry Cycloaddition Reactions
- Healthcare Systems and Reforms
Beijing Normal University
2023
Sichuan University
2019-2023
State Key Laboratory of Biotherapy
2021
Abstract Isobenzofulvene species are versatile synthons in organic chemistry, which have been employed diverse challenging higher‐order cycloaddition reactions. Here, the first chemoselective and asymmetric cross [10+2] reaction between activated 2‐alkylidene‐1‐indanones a variety of electron‐deficient alkenes has developed, relying on situ generation dearomative 1‐hydroxyl isobenzofulvene anion intermediates under catalysis newly designed bulky cinchona‐derived phase‐transfer compound. An...
Here we report that Morita-Baylis-Hillman carbonates from diverse aldehydes and methyl vinyl ketones can be directly utilised as palladium-trimethylenemethane 1,4-carbodipole-type precursors, both reactivity enantioselectivity are finely regulated by adding a chiral ammonium halide the ion-pair catalyst. The newly assembled intermediates, proposed to contain an electronically neutral π-allylpalladium complex reactive compact ion pair, efficiently undergo asymmetric [4 + 2] annulations with...
A double catalytic system combining 2-mercaptobenzoic acid and a chiral phase transfer substance was disclosed for the intermolecular cross Rauhut–Currier reaction of 2-cyclopentenone isatin-based alkylidene malononitriles. The resulting adducts were sequentially assembled with diverse electron-deficient olefins to furnish highly enantioenriched cyclohexane derivatives (up 96:4 er, >19:1 dr). similar quinine further developed α-cyano chalcones 96.5:3.5 er).
An asymmetric intramolecular Rauhut–Currier reaction of linear bis(enones) has been achieved via double activation catalysis thiols and phase transfer substances, furnishing both enantioenriched cyclohexene cyclopentene derivatives (up to 95% ee). Furthermore, the desymmetric version prochiral substrates was developed under similar catalysis, producing frameworks bearing an additional tertiary or even quaternary stereogenic center with moderate excellent diastereo- enantioselectivity ee, >19:1 dr).
Reducing health inequities for migrants is a huge challenge shared globally. Based on big data of China Migrants Dynamic Survey in 2017, this paper applied Ordered Logit models and to examine the effect education migrants. Propensity score matching instrumental variable were also employed solve endogenous problem. This found significant promotion migrants, which remained after series robustness check. Further analysis showed that consultative more effective than nonconsultative education....