A5100951804- Covalent Organic Framework Applications
- Advanced Photocatalysis Techniques
- Advanced oxidation water treatment
- Fuel Cells and Related Materials
- Educational Reforms and Innovations
- Technology Assessment and Management
- Electrochemical Analysis and Applications
- Regional Development and Environment
- Luminescence and Fluorescent Materials
- Quality and Management Systems
- Metal-Organic Frameworks: Synthesis and Applications
- HIV/AIDS drug development and treatment
- Perovskite Materials and Applications
- Medical Research and Treatments
- Biochemical and Molecular Research
- Cancer therapeutics and mechanisms
Dongguan University of Technology
2024
University of Science and Technology of China
2024
Tianjin University
2024
State Key Laboratory of Biotherapy
2023
Sichuan University
2023
Covalent organic frameworks (COFs) have potential applications in a wide range of fields. However, it remains critical challenge to constrain their covalent expansions the one-dimensional (1D) direction. Here, we developed general approach fabricate 15 different highly crystalline COFs with zigzag-packed 1D porous chains through condensation V-shaped ditopic linkers and X-shaped tetratopic knots. Appropriate geometrical combinations scope knots distinct aromatic cores, linkages,...
Abstract Five types of novel glycoconjugated 7-ethyl-10-hydroxycamptothecin (SN38) derivatives were synthesized to evaluate their anti-tumor activity against HCT116 human colon cancer cells, and the results showed that all them demonstrated potent activity. Notably, glucose galactose conjugates exhibited better activity, while mannose allose had slightly lower Our findings suggested SN38 was affected by type modifying molecule used position modification. These could have implications for...