A5009587552- Renal Diseases and Glomerulopathies
- Astronomy and Astrophysical Research
- Reproductive System and Pregnancy
- Pancreatic function and diabetes
- Dermatological and Skeletal Disorders
- Diabetes and associated disorders
- Kidney Stones and Urolithiasis Treatments
- Chronic Kidney Disease and Diabetes
- MicroRNA in disease regulation
- Systemic Lupus Erythematosus Research
- Inflammatory Biomarkers in Disease Prognosis
- Stellar, planetary, and galactic studies
- Adaptive optics and wavefront sensing
- Dialysis and Renal Disease Management
- Cancer-related molecular mechanisms research
- Mitochondrial Function and Pathology
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- RNA modifications and cancer
- Genetic and Kidney Cyst Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism, Diabetes, and Cancer
- Bariatric Surgery and Outcomes
Qingdao Municipal Hospital
2020-2025
Qingdao University
2020-2025
Affiliated Hospital of Qingdao University
2022
University of Science and Technology of China
1998
Objective Diabetic kidney disease (DKD) is the most common chronic (CKD) and has highest prevalence of end-stage (ESKD) globally, owing mostly to rise in Type 2 diabetes mellitus (T2DM) correlated with obesity. Current research suggested that immune response inflammation may play a role pathophysiology T2DM. The systemic immune-inflammation index (SII) novel integrated inflammatory biomarker not yet been linked DKD. We aimed identify potential relationship between SII Methods In National...
Chronic kidney disease (CKD) is a severe clinical syndrome with significant socioeconomic impact worldwide. Orderly energy metabolism essential for normal function and disorders are increasingly recognized as an important player in CKD. Energy characterized by ATP deficits reactive oxygen species increase. Oxygen mitochondria production, hypoxia mitochondrial dysfunction both affect the production process. Renin-angiotensin adenine signaling pathway also play regulatory roles metabolism. In...
Enteric hyperoxaluria is a common cause of secondary oxalate nephropathy (ON), and pancreatic exocrine insufficiency (PEI) one the causes enteric hyperoxaluria. Due to atypical clinical symptoms or elusive etiology, incidence PEI often underestimated. For patients with ON, it crucial screen for its etiology. Cases pathological diagnosis ON acute kidney injury (AKI) during January 2023 December were retrospectively enrolled. The datasets manifestation, pathology, treatment, prognosis...
In present paper we have proposed an optical fiber positioning system for LAMOST (Large Sky Area Multi-Object Fiber Spectroscopy Telescope). this system, the convex focal plate of telescope (Its diameter is 1.75 m) divided into about 4000 individual domains. Each domain contains a controllable unit which named X-unit. specified with position its polar coordinates (the angle and radius distance from center) by using center point as reference. X-unit can be moved smoothly verifying two...
Long noncoding RNA (lncRNA) (GABPB1-IT1) has been reported to be downregulated in lung cancer, while its expression and function other cancers are unknown. In this study, the levels of GABPB1-IT1 tissue samples from 62 ccRCC patients were measured by performing RT-qPCR. Potential base pairing formed between miR-21 was explored using online program IntaRNA 2.0 further confirmed Dual-luciferase activity assay pulldown assay. The role regulating PTEN evaluated RT-qPCR Western blot. GABPB1-IT1,...
Abstract Background Previous studies have reported SIRT1 was inversely modulated by miR‐34a, However, mechanism of metformin (MFN)'s renal podocyte protection under high glucose (HG) conditions and the connection between miR‐34a expression in diabetic nephropathy (DN) remain unclear. Method We aimed to further elucidate role HG‐treated podocytes DN. A conditionally immortalized human cell line cultivated d ‐glucose (30 mM). Results Microarray RT‐qPCR revealed that downregulated podocytes....
Background Podocytes, as intrinsic renal cells, can also express MHC-II and costimulatory molecules under inflammatory conditions, suggesting that they may act antigen-presenting cells (APCs) to activate immune cell responses then lead immune-mediated injury. They are already recognized main targets in the pathogenic mechanism of hepatitis B virus (HBV)-associated glomerulonephritis (HBV-GN). Previous studies have indicated infiltration tissue injury evident kidney samples patients with...