Weiguo Wan

ORCID: 0009-0008-2619-4401
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About
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Research Areas
  • Nuclear Receptors and Signaling
  • Angiogenesis and VEGF in Cancer
  • Apelin-related biomedical research
  • Systemic Lupus Erythematosus Research
  • Anesthesia and Neurotoxicity Research
  • Healthcare cost, quality, practices
  • Congenital heart defects research
  • Healthcare Policy and Management
  • Gout, Hyperuricemia, Uric Acid
  • Ultrasound in Clinical Applications
  • Urticaria and Related Conditions
  • Renal function and acid-base balance
  • Adrenal Hormones and Disorders
  • Mesenchymal stem cell research
  • Chronic Lymphocytic Leukemia Research
  • Monoclonal and Polyclonal Antibodies Research
  • Exercise and Physiological Responses
  • Rheumatoid Arthritis Research and Therapies
  • Systemic Sclerosis and Related Diseases
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Sphingolipid Metabolism and Signaling
  • Autoimmune Bullous Skin Diseases
  • Galectins and Cancer Biology

Huashan Hospital
2021-2025

Fudan University
2021-2025

Northeast Ohio Medical University
2022-2023

Many clinical trials have attempted to use stem cells treat ischemic heart diseases (IHD), but the benefits been modest. Though coronary collaterals can be a “natural bypass” for IHD patients, regulation of collateral growth (CCG) and role endogenous in CCG are not fully understood. In this study, we used bone marrow transplantation scheme study (BMSCs) rat model CCG. Transgenic GFP rats were trace BMSCs after transplantation; was harvested or sorted transplantation. After recovering from...

10.3390/cells12020242 article EN cc-by Cells 2023-01-06

Objective To analyze the roles of B-cell ccaffold protein with ankyrin repeats 1 (BANK1)in collagen-induced arthritis (CIA) murine model and correlation disease severity. Methods CIA were established evaluated. In different stages, serum levels anti-CⅡ auto-antibodies BANK1 detected by electrochemiluminescence immunoassay(ELISA). Moreover, expression mRNA in peripheral blood cells real-time polymerase chain reaction (PCR) its clinical scores was analyzed. Then percentage B spleen...

10.3760/cma.j.issn.1007-7480.2018.01.007 article EN Chin J Rheumatol 2018-01-15

- Coronary collateral growth is a natural bypass for ischemic heart diseases. It offers tremendous therapeutic benefit, but the process of coronary incompletely understood due to limited preclinical murine models that would enable interrogation its mechanisms and processes via genetic modification lineage tracing. Understanding by which collaterals develop can unlock new strategies disease.- To model repetitive ischemia (RI) investigate in adult hearts tracing.- A was developed using short...

10.1096/fasebj.2022.36.s1.r5649 article EN The FASEB Journal 2022-05-01

Abstract Objective: Gout is a common arthritis caused by deposition of monosodium urate crystals. Macrophage crucial in the process (MSU) -induced inflammation. Although it has been reported that adrenocorticotropic hormone (ACTH) nature can be used to cure urarthritis, mechanism concerning macrophage still not clear. This study aims explore how natural ACTH alleviate urarthritis through functional changes macrophage. Methods: We analysed variations VAS pain scores five patients, knowing...

10.21203/rs.3.rs-797094/v1 preprint EN cc-by Research Square (Research Square) 2021-08-20
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