A5087181884- Advanced Combustion Engine Technologies
- Combustion and flame dynamics
- Advanced Aircraft Design and Technologies
- Heat transfer and supercritical fluids
- Vehicle emissions and performance
- Radiative Heat Transfer Studies
- Biodiesel Production and Applications
- Electrohydrodynamics and Fluid Dynamics
- Catalytic Processes in Materials Science
- Rocket and propulsion systems research
- Chemical Thermodynamics and Molecular Structure
- Atmospheric chemistry and aerosols
- Thermal and Kinetic Analysis
- Air Quality and Health Impacts
- Geological formations and processes
- Fire dynamics and safety research
- Fluid Dynamics and Heat Transfer
- Meningioma and schwannoma management
- Advanced Control Systems Optimization
- Particle Dynamics in Fluid Flows
- Pesticide and Herbicide Environmental Studies
- Spectroscopy and Laser Applications
- Power Transformer Diagnostics and Insulation
- Combustion and Detonation Processes
- Lubricants and Their Additives
Oklahoma State University Medical Center
2025
University of Oklahoma Health Sciences Center
2025
Ipsen (United Kingdom)
2023
Loma Linda University
2023
University of Sheffield
2005-2015
Sandia National Laboratories California
2015
University of Oklahoma
2012
Qinetiq (United Kingdom)
2002-2005
University of Leeds
2003-2005
Carl Zeiss (United States)
2003
Abstract Background Meningiomas exhibit considerable clinical and biological heterogeneity. We previously identified four distinct molecular groups (immunogenic, NF2-wildtype, hypermetabolic, proliferative) that address much of this Despite the utility these groups, stochasticity clustering methods use multi-omics data for discovery limits potential classifying prospective cases. sought to with a dedicated classifier. Methods Using an international cohort 1698 meningiomas, we constructed...
A cradle-to-grave life cycle assessment (LCA) of structural aircraft materials has been utilised to assess and compare the total emissions produced during manufacturing, use disposal aerospace their selected components.First, a comparison aluminium, GLARE carbon fibre reinforced polymer (CFRP) plates was performed investigate potential lightweight composites in reducing aviation emissions.Subsequently, case study is presented on tubular component for which more accurate manufacturing data...
Growing concern over emissions from increased airport operations has resulted in a need to assess the impact of aviation related activities on local air quality and around airports, develop strategies mitigate these effects. One such strategy being investigated is use alternative fuels aircraft engines auxiliary power units (APUs) as means diversify fuel supplies reduce emissions. This paper summarizes results study characterize an APU, small gas turbine engine, burning conventional Jet A-1,...
Hygroscopic properties of combustion particles were measured online with a Hygroscopicity Tandem Differential Mobility Analyzer (H‐TDMA) during PartEmis jet engine combustor experiments. The was operated at old and modern cruise conditions fuel sulfur contents (FSC) 50, 410 1270 μg g −1 , hygroscopic growth factors (HGF) different dry diameters investigated relative humidities RH ≤ 95%. HGFs increased strongly increasing FSC (HGF[95% RH, 50 nm, cruise] = 1.01 1.16 for low high FSC,...
INTRODUCTION: Treatment of the tumor and dural margin, most commonly with surgery sometimes radiation, are cornerstones therapy for meningioma. Molecular classifications have provided insights into biology disease. However, response to treatment remains heterogeneous. METHODS: Data were collected from 10 different institutions. Meningiomas re-graded in accordance 2021 WHO classification stratified Groups based on previously published methodologies utilizing DNA methylation alone or combined...
Abstract Background: TERT promoter mutation (TPM) is a rare but established biomarker in meningiomas associated with aberrant expression, reduced progression-free survival (PFS), and overall survival. While highly expressed tumors promotor mutations, its expression has also been observed even wildtype promoters (TP-WT). This study aimed to assess the prevalence of association clinical outcome meningiomas. Methods: Bulk RNA sequencing (n=604), Sanger (n=1095), methylation profiling (n=1218)...
Numerical modeling has become an essential tool in combustion research as a means of predicting performance and pollutant formation, e.g., NO x soot. In many models the commercial fuel such kerosene been represented by single-step empirical expressions. To predict kinetically controlled phenomena, more detailed chemical kinetic reaction mechanism is required. This paper reports development for kerosene, where, purposes modeling, assumed to be 89%n-decane 11% toluene. The initially validated...
The work characterizes the changes in volatile and semivolatile PM emissions from a gas turbine engine resulting burning alternative fuels, specifically gas-to-liquid (GTL), coal-to-liquid (CTL), blend of Jet A-1 GTL, biodiesel, diesel, to standard A-1. data presented here, compares mass spectral fingerprints different fuels as measured by Aerodyne high resolution time-of-flight aerosol spectrometer. There were three sample points, two at exhaust exit plane with dilution added locations...
Peristaltic pumping during bioprocessing can cause therapeutic protein loss and aggregation use. Due to the complexity of this apparatus, root-cause mechanisms behind have been long sought. We developed new methodologies isolating various peristaltic pump determine their effect on monomer loss. Closed-loops tubing were used investigate effects parameters temperature loss, whilst two mechanism isolation are isolate occlusion lateral expansion-relaxation tubing. Heat generated heat-induced...
Abstract With changes in the availability and quality of existing aviation fuels anticipated next 30 years it is timely to assess how fuel properties would affect range payload performance aircraft. The effects on a wide candidate for are investigated, including blends conventional hydrocarbon fuels. Lighter tend be more desirable commercial flights, where flight as close maximum possible. Flights favouring over better suited by dense fuel. suggest each aircraft, an optimum may exist...
One of the crucial aspects in adoption alternative fuels (e.g., GtL fuel) aviation industry is to investigate their compatibility with elastomeric materials used current gas turbine engines. This study employed stress relaxation technique effects three solvents, namely, decalin (cycloparaffin), n-decane (normal paraffin), and ShellSol T solvent (isoparaffins) on O-rings made from different materials. Results indicated that both fluorosilicone fluorocarbon showed excellent all 25 blends...
Computer-based Life Cycle Analysis (LCA) models were carried out to compare lightweight composites with the traditional aluminium over their useful lifetime. The analysis included raw materials, production, life in operation and disposal at end of material's life. carbon fibre epoxy resin composite could some cases reduce weight a component by up 40 % compared aluminium. As fuel consumption an aircraft is strongly influenced its total weight, emissions can be significantly reduced increasing...
Abstract This paper describes the current status of knowledge regarding impact aviation on atmosphere. The growth industry is likely to continue in future and at present there are significant concerns that this will adversely affect climate local air quality vicinity airports. Indeed, it possible may become a constraint increased capacity some large hub Currently radiative forcing from aircraft emissions, other than CO 2 , not accounted for International Civil Aviation Organization emission...
Lean premixed prevaporised (LPP) combustion can reduce NOx emissions from gas turbines, but often leads to instability. A flame transfer function describes the change in rate of heat release response perturbations inlet flow as a frequency. It is quantitative assessment susceptibility disturbances. The resulting fluctuations will turn generate more acoustic waves and some situations self-sustained oscillations result. Flame functions for LPP are poorly understood at present crucial...
This study describes the development of a new binary encoded genetic algorithm to determine subset species and their associated reactions that best represent full starting point reaction mechanism in modeling low-pressure stoichiometric 12.5% CH4/25% O2/62.5% Ar, burner-stabilized premixed flame. The number chosen is kept fixed specified at start procedure. chooses better mechanisms on basis an objective function which measures how well reduced predict set species' profiles simulated by...
This paper describes Pantobot-3D, a vision-based monitoring system for rail pantograph inspection developed by Camlin Italy srl, part of Group. The is based on an automatic algorithm able to provide: fully three-dimensional representation the using stereo cameras, model classification, and integrity assessment main components, e.g. horns strips. provides details architecture, overview each functionality performance. Presently, two installations Pantobot-3D are mainline Italian High Speed...
In this study a genetic algorithm (GA) approach for determining new reaction rate parameters ( A , g and E in the non-Arrhenius expressions) combustion of hydrogen/air mixture perfectly stirred reactor (PSR) is assessed. floating-point coded GA fitness function have been developed that dramatically increase both convergence predictive accuracy algorithm, thus promising extension method to more detailed schemes. Output profiles species 20 sets PSR conditions, obtained from an original set...
Gaseous S(VI) (SO 3 + H 2 SO 4 ) has been measured by chemical ionization mass spectrometry (CIMS) in the simulated internal flow of an aircraft gas turbine a test rig at ground level during PartEmis 2002 campaign. Building on and calculated total sulfur S T abundance ratio ε = S(VI)/S was determined. The measurements to be reported here were made two sampling points, for engine conditions representative old modern cruise fuel content FSC 1270 ppm. For both increased with increasing exhaust...