A5102828940- Advanced Drug Delivery Systems
- Protein purification and stability
- Dialysis and Renal Disease Management
- Hepatitis B Virus Studies
- Vaccine Coverage and Hesitancy
- Viral gastroenteritis research and epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
- Animal Virus Infections Studies
- Food Allergy and Anaphylaxis Research
- Blood properties and coagulation
- Monoclonal and Polyclonal Antibodies Research
- Bacterial Infections and Vaccines
- Platelet Disorders and Treatments
- Microencapsulation and Drying Processes
- Inhalation and Respiratory Drug Delivery
Sanofi (United States)
2022
Sanofi (Canada)
2013-2021
Abstract: Forced degradation studies are typically conducted during the early development phase of vaccine candidates to obtain information on potential pathways, support analytical methods development, and identify stabilizers optimal conditions for long-term storage. The regulatory guidelines forced regarding biologics have few no procedural instructions how approach studies. In this review, we provide an overview used study in vaccines, mechanisms degradation, methodology, examples...
Background Point-of-care (PoC) testing of platelet count (PLT) provides real-time data for rapid decision making. The goal this study is to evaluate the accuracy and precision counting using a new microvolume (8 μL), absolute counting, 1.5 kg cytometry-based blood analyzer, rHEALTH ONE (rHEALTH) in comparison with International Society Laboratory Hematology (ISLH) method, which uses cytometer an impedance analyzer. Methods Inclusion eligibility were healthy adults (M/F) ages 18–80 donation...
Vaccine formulations may contain visible and/or subvisible particles, which can vary in both size and morphology. Extrinsic are particles not part of the product such as foreign contaminants, generally considered undesirable should be eliminated or controlled injectable products. However, biological products, particular vaccines, also that inherent to product. Here we focus on characterization a live, replication-deficient viral vaccine candidate against HSV genital herpes an early...