Interleukin-23 (IL-23) is a conventional proinflammatory IL related to colorectal carcinoma (CRC). The signal transducer and activator of transcription (STAT) suppressors cytokine signaling (Socs) molecules, respectively, serve as agonists antagonists IL-23-associated inflammation. However, it remains unknown whether IL-23 directly affects CRC metastasis. In this study, we measured the metastasis several human cell lines stimulated by in vitro vivo. Interestingly, prometastasis effect was...

Research on electrical load simulator (ELS) which is directly driven by permanent magnet synchronous motor (PMSM), and build up mathematical model of ELS. Analyze the couple relationship between torque actuator, generating mechanism extraneous in ELS, conclude that related to velocity so propose velocity-loop compensation algorithm eliminate Aiming at requirement high frequency response kinds nonlinear factors traditional PID control theory cannot meet demand accuracy, research fuzzy with...

3D integration is a promising technology that provides high memory bandwidth, reduced power, shortened latency, and smaller form factor. Among many issues in IC design production, testing remains one of the major challenges. This paper introduces new design-for-test technique called 3D-GESP, an efficient Built-In-Self-Repair (BISR) algorithm to fulfill test reliability needs for 3D-stacked memories. Instead local redundancy allocation method as most current BISR techniques employed, we...

To improve the working performance of early annular jet pump (EAJP), a streamlined (SAJP) was proposed. The flow field and EAJP SAJP with an area ratio (m) 1.75 were numerically studied compared, separately, by using combination Realizable k-ε turbulence model Schnerr–Sauer cavitation model. results show that efficiency is higher than EAJP, when (q) 0.30, maximum increase 1.2%. Furthermore, high-efficiency (q = 0.40~0.69) wider 0.36~0.57). There no separation low local pressure in SAJP, due...

To find the influence of suction chamber and throat inlet profiles on cavitation performance an annular jet pump (AJP), a numerical method using combination realizable k–ϵ turbulence model Schnerr–Sauer was applied. This paper comprehensively studied AJPs with polygonal line profile (POL) streamlined (STR). The results showed that efficiency (η) can be increasedby STR largest increase 1.4%. Since is smoothly connected in AJP STR, flow separation local low pressure did not appear. critical...

Abstract Jet pump is a kind of fluid machinery, which uses jet shear and turbulent diffusion to transfer mass energy. It widely used in water project, civil engineering other fields. In order investigate the influence suction chamber profile on flow field annular pump, conical streamlined were compared by applying turbulence numerical simulation method. The performance, pressure characteristics, velocity energy distributions pumps with two chambers are analysed. calculation shows that...

This paper focuses on a robust control method applied to an electro-Hydraulic Load Simulator (HLS) acting special aerodynamic load. Owing the high-speed on-off valve, some pneumatic aircraft actuators have inherent high-frequency motion disturbance that reduces dynamic tracking performance. Through combining velocity synchronising decoupling compensation and equivalent observers, this presents Dynamic Robust Compensation (DRC) achieve high precision load simulation. The experiments indicate...

Along with the progress of rating and signal processing technology, because its advantages wide application, grating measuring technology has become a research hotspot in precision field. Nanometer urgently to solve problem need industrial development scientific from sub micrometer nanometer measurement. This paper systematically discusses status, existing problems, developing trends other issues about technology. It provides references researches development.

In order to study how strengthen the connection between widened and old part of a highway subgrade, so as avoid an impermissible differential settlement at interface two parts three sections experimental embankment were constructed in rebuilding project Lasa-Rikaze Highway by placing geogrid layers horizontally embankment. After completion widening, series resilient modulus tests carried out field. The test results proved that reinforcement is efficient method connection. When filled with...

Unlike traditional methods, the entropy production method provides a quantitative and intuitive framework for understanding spatial distribution of energy losses. This study employs to analyze flow loss characteristics six-nozzle Pelton turbine at various operating heads. The results affirm that stands as viable approach evaluating losses in turbine. Within turbine, increased rate primarily from wall friction, secondary flow, separation, jet expansion, impact, interference. Under varying...

In order to improve the ultimate performance of Light-Duty Load Simulator, a design with electro-hydraulic loading scheme is discussed in this paper. Some key points mechanism Electro-Hydraulic Simulator (HLS) are researched and revealed. Based on analysis mathematical model control strategy, compound controller including disturbance observer, fuzzy-PID velocity synchronizing decoupling compensation designed. Results experiments show that improves system. application special aircraft...

Length–weight relationships (LWRs) are presented for 11 species [Acrossocheilus monticola (Günther, 1888), Squalidus wolterstorffi (Regan, 1908), Sinibrama taeniatus (Nichols, 1941), Gnathopogon herzensteini 1896), Rhynchocypris oxycephalus (Sauvage & Dabry de Thiersant, 1874), Rhodeus lighti (Wu, 1931), Platysmacheilus nudiventris Luo, Le Chen, 1977, Hemibagrus macropterus Bleeker, 1870, Glyptothorax fokiensis (Rendahl, 1925), Liobagrus marginatoides 1930), Sinogastromyzon szechuanensis...

To meet the needs of saving energy for high pressure and power airborne electro-hydraulic servo actuation system, adopting different systems according to flight missions may be useful. This paper describes mathematic models 21MPa system 35MPa simulates with MATLAB/Simulink. The simulation obtains perfect dynamic performances detailed comparison results about efficiency. Then simulate F16 model pressures. show influence performance is almost same as that 35MPa; verify more energy.

The training of deep learning models is inseparable from sufficient data as the driving force. However, in power transmission model task, it very difficult and expensive to obtain samples, so augmentation has become a common means increasing samples. In recent years, various generative have demonstrated strong sample generation capabilities different modalities, especially adversarial networks (GANs) made important progress synthesizing compelling image audio traditional GAN faces...

This paper aims to explore the turbulence features of jet flow field in mine stopes.For this purpose, a chamber model was established at scale 1/20 based on similarity criterion.Then, author obtained average maximum length, width and corresponding position, as well turbulent diffusion coefficient angle.Focusing velocity field, distribution intensity, skewness, flatness Reynolds stress crosssection were also acquired research.The results show that region belongs main airflow area when air...

Abstract Aiming at the problems of large leakage and high friction heat generation piston ring under pressure speed, based on previous research V-shaped groove ring, design method is carried out in depth. The numerical analysis focusing number grooves depth ring. influence law verified analyzed by using a high-pressure high-speed rotating test bench. simulation experimental results show that 4 8 reduced 14.9 28.5%, temperature 10.9 4.7%; When there are 28.5 21.7%; when 0.04 0.08 mm, 4.1%....