Upinder Singh

ORCID: 0009-0009-3908-2481
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Research Areas
  • Natural Fiber Reinforced Composites
  • Synthetic Organic Chemistry Methods
  • Polymer Nanocomposites and Properties
  • Chemical Synthesis and Analysis
  • Chronic Myeloid Leukemia Treatments
  • PI3K/AKT/mTOR signaling in cancer
  • Chemical Synthesis and Reactions
  • Cerebral Palsy and Movement Disorders
  • Orthopedic Surgery and Rehabilitation
  • Metallurgy and Material Forming
  • Aluminum Alloys Composites Properties
  • Cloud Computing and Resource Management
  • Bone fractures and treatments
  • biodegradable polymer synthesis and properties
  • Atherosclerosis and Cardiovascular Diseases
  • Protein Kinase Regulation and GTPase Signaling
  • Transcranial Magnetic Stimulation Studies
  • Additive Manufacturing and 3D Printing Technologies
  • Polymer Foaming and Composites
  • Cell Image Analysis Techniques
  • Digital Imaging for Blood Diseases
  • COVID-19 diagnosis using AI
  • Lower Extremity Biomechanics and Pathologies
  • Structural Behavior of Reinforced Concrete
  • Retinoids in leukemia and cellular processes

All India Institute of Medical Sciences
2012-2024

All India Institute of Medical Sciences Bhopal
2024

All India Institute of Medical Sciences Raipur
2024

Post Graduate Institute of Medical Education and Research
2022

Punjab Engineering College
2018

Central Institute of Plastics Engineering and Technology
2008

York University
2001

Eli Lilly (United States)
1996-2000

Case Western Reserve University
1994-1997

Cleveland Foundation
1997

Protein kinase C (PKC) is a family of closely related serine and threonine kinases. Overactivation some PKC isozymes has been postulated to occur in several diseases states, including diabetic complications. Selective inhibition overactivated may offer unique therapeutic approach disease states such as retinopathy. A novel series 14-membered macrocycles containing N-N'-bridged bisindolylmaleimide moiety described. panel eight cloned human (alpha, beta I, II, gamma, delta, epsilon, sigma,...

10.1021/jm950588y article EN Journal of Medicinal Chemistry 1996-01-01

The expansion of kinase assay technologies over the past decade has mirrored growing interest in kinases as drug targets. As a result, there is no shortage convenient, fluorescence-based methods available to targets that span kinome. authors recently reported on development non-activity-based characterize inhibitors depended displacement an Alexa Fluor 647 conjugate staurosporine (a "tracer") from particular kinase. Kinase were characterized by change fluorescence lifetime tracer when it was...

10.1177/1087057109339207 article EN cc-by-nc-nd SLAS DISCOVERY 2009-06-30

The human pregnane X nuclear receptor (PXR) is a xenobiotic-regulated that activated by range of diverse chemicals, including antibiotics, antifungals, glucocorticoids, and herbal extracts. PXR has been characterized as an important in the metabolism xenobiotics due to induction cytochrome P450 isozymes activation large number prescribed medications. Developing methodologies can efficiently detect ligands will be clinically beneficial avoid potential drug–drug interactions. To facilitate...

10.1089/adt.2009.193 article EN Assay and Drug Development Technologies 2009-04-01

Free-radical oxidation of human low-density lipoprotein (LDL) produces levuglandin (LG)-protein adducts that were detected with an enzyme-linked immunosorbent assay using LGE2-KLH antibodies which recognize LGE2-derived pyrroles. The level immunoreactivity increases time and reaches a maximum by 8 h. yield pyrrole varies nonlinearly the LG adduction to LDL. At low LG:LDL ratios, such as those in oxidized LDL, reaction primary amino groups LGE2 mostly non-pyrrole are not immunoreactive....

10.1021/tx970016b article EN Chemical Research in Toxicology 1997-07-01

Work-related Neck Pain (WRNP) is a leading cause of disability and absenteeism. There dearth information about burden determinants WRNP in health facility setting India.A cross-sectional study was carried out at tertiary care hospital New Delhi. All Group C desk job workers involved the administrative work were included study. Participants screened for by using pretested semi-structured questionnaire. Detailed on probable risk factors collected among patients with WRNP. examination trained...

10.4103/0970-0218.170967 article EN cc-by-nc-sa Indian Journal of Community Medicine 2015-12-03

There is a crucial need to devise optimum rehabilitation programs for children with cerebral palsy (CP).This study aimed assess the feasibility, safety, and efficacy of combining 6-Hz primed, low-frequency, repetitive transcranial magnetic stimulation (rTMS) modified constraint-induced movement therapy (mCIMT) in improving upper limb function unilateral CP.Children aged 5 18 years CP were randomized (23 each arm) receive 10 sessions mCIMT real rTMS (intervention or sham (control arm), on...

10.1177/15459683231174222 article EN Neurorehabilitation and neural repair 2023-05-01

10.14445/22312803/ijctt-v11p137 article EN International Journal of Computer Trends and Technology 2014-05-25

Objectives: Children are most frequently affected by urinary tract infections (UTIs). Urine dipsticks along with use in urine routine testing can help predicting UTI. In this study we aim to evaluate the utility of individual and combination dipstick parameters, including nitrite leukocyte esterase (LE), against gold standard culture for detection UTI among pediatric outpatients. Materials Methods: Nine hundred forty-nine samples from January 2021 December were cultured on Cysteine Lactose...

10.25259/jlp_2_2023 article EN cc-by-nc-nd Journal of Laboratory Physicians 2024-02-19

Background: The microscopic examination of peripheral blood film is labour-intensive, subjective and time-consuming. It also requires trained technical staff. Technological advancements have been made to develop automated morphological analytical systems for the classification both red cells white cells. We aimed investigate ability microscopy system AI100 with ShonitTM examine films. Methods: study was a prospective done at All India Institute Medical Sciences, New Delhi. compared analysis...

10.23958/ijirms/vol09-i07/1931 article EN cc-by International Journal of Innovative Research in Medical Science 2024-07-24

ABSTRACT Objectives To study the additional benefits of ultrasonography in patients with inferior heel pain treated diclofenac for foot pressure profile and pain. Materials methods This was a randomized experimental trial. Comparison efficacy two treatment modalities (diclofenac alone vs ultrasound therapy) respect to profiles using pedography visual analog scale (VAS) carried out. Twenty-three unilateral were considered subjects. The main outcome measures severity VAS. Results In group, it...

10.5005/jp-journals-10066-0002 article EN Indian Journal of Physical Medicine and Rehabilitation 2017-01-01

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.200104105 article EN ChemInform 2001-01-23

Aim: Footwear modification with lateral elevation in the sole is considered an easy to administer and low-cost orthotic intervention for knee osteoarthritis, yet it not routinely prescribed because of limited available data prove its effectiveness.This study aimed assess effect wedging footwear, quantitatively.Materials methods: We used Zebris Foot pressure platforms integrated into Gait Analysis Laboratory foot assessment.A Prospective Pre-Post Interventional Study was conducted 40 patients...

10.5005/jp-journals-10040-1243 article EN cc-by-nc Journal of Foot and Ankle Surgery (Asia Pacific) 2022-10-07

➢ Polyurethane-based composite with carbon fibre (PUCFs) their historical date and research status are summarized.➢ By using bibliometrics analysis-providing Quantitative Qualitative evidence.➢ PCFs is reviewed based on geographical

10.30780/specialissue-icaaset021/018 article EN International Journal of Technical Research & Science 2021-06-15
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