H Sehgal

ORCID: 0009-0009-4561-6523
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About
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Research Areas
  • Hemoglobin structure and function
  • Viral gastroenteritis research and epidemiology
  • Diphtheria, Corynebacterium, and Tetanus
  • Hemoglobinopathies and Related Disorders
  • Botulinum Toxin and Related Neurological Disorders
  • Erythropoietin and Anemia Treatment
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Blood transfusion and management
  • Escherichia coli research studies
  • Hemodynamic Monitoring and Therapy
  • Intramuscular injections and effects
  • Infectious Encephalopathies and Encephalitis
  • Neuroscience of respiration and sleep
  • Pediatric Pain Management Techniques
  • Pharmacological Effects and Toxicity Studies
  • Renal function and acid-base balance
  • Viral Infections and Immunology Research
  • Thermal Regulation in Medicine
  • Blood donation and transfusion practices
  • Epilepsy research and treatment
  • Hematological disorders and diagnostics
  • Cardiac Arrest and Resuscitation
  • Heme Oxygenase-1 and Carbon Monoxide
  • Bacterial Infections and Vaccines
  • Electrolyte and hormonal disorders

University of Liverpool
2024

Mercy Hospital and Medical Center
1987-1990

University of Chicago
1987-1988

Lady Hardinge Medical College
1985

Kalawati Saran Children's Hospital
1985

The risks of transfusion‐associated infectious disease have led to a reassessment transfusion practice, which in turn has resulted trend toward the reduction homologous transfusion. This is primarily due initiation hemotherapy at more severe levels anemia. optimum threshold for therapy, or trigger (TT), unknown. purpose this study evaluate effects withholding lowering TT hematocrit (Hct) 15 percent unanesthetized animals. Nineteen adult baboons underwent laparotomy simulate surgical stress....

10.1046/j.1537-2995.1990.30190117621.x article EN Transfusion 1990-01-01

The risks associated with the administration of blood products have increased efforts to avoid homologous transfusions. Preoperative autologous donation has received renewed interest as a method decreasing transfusion requirements. Autologous donations may also stimulate postoperative erythropoiesis. purpose this study is evaluate effect an aggressive program on Ten adult male baboons were divided into two groups. group (n = 5) donated average 2 units per week for 5 weeks before operation....

10.1046/j.1537-2995.1990.30490273433.x article EN Transfusion 1990-05-01

AbstractPolymerization of SFH-P currently provides the only approach that leads to a hemoglobin solution approximates O2 carrying capacity whole blood and can be infused without altering COP plasma. It appears have an adequate loading unloading characteristic greatly improved intravascular half-life. In addition, stable shelf-life at 4°C greater than five months, makes it prime candidate for future pre-clinical clinical investigations.

10.3109/10731198809132567 article EN Biomaterials Artificial Cells and Artificial Organs 1988-01-01

Hemoglobin solutions are undergoing clinical trials as erythrocyte substitutes. Some of these have higher O2 affinities compared with normal hemoglobin. Also, they appear to interact endothelial-derived smooth muscle relaxation. The purpose this study was evaluate the nature and limits compensation acute normovolemic anemia in erythrocyte-free primate maintained a hemoglobin solution. experimental group consisted six anesthetized paralyzed adult baboons (Papio anubis) that were exchange...

10.1152/jappl.1990.68.3.938 article EN Journal of Applied Physiology 1990-03-01

Journal Article Sensitivity of the IL 282 Co-oximeter to low hemoglobin concentration and high proportions methemoglobin. Get access H L Sehgal, Sehgal Search for other works by this author on: Oxford Academic Google Scholar R A Rosen, Rosen DeWoskin, DeWoskin S Gould, Gould G Moss Clinical Chemistry, Volume 26, Issue 2, 1 February 1980, Pages 362–363, https://doi.org/10.1093/clinchem/26.2.362 Published: 01 1980

10.1093/clinchem/26.2.362 article EN Clinical Chemistry 1980-02-01

Journal Article Performance of the Oxygen-Hemoglobin Dissociation Analyzer (“Hemo-O-Scan”), compared with IL 282 Co-Oximeter. Get access H L Sehgal, Sehgal Search for other works by this author on: Oxford Academic Google Scholar R A Rosen, Rosen DeWoskin, DeWoskin S Gould, Gould G Moss Clinical Chemistry, Volume 26, Issue 6, 1 May 1980, Page 784, https://doi.org/10.1093/clinchem/26.6.784 Published: 01 1980

10.1093/clinchem/26.6.784 article EN Clinical Chemistry 1980-05-01
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