A5101689336- Healthcare Policy and Management
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- BRCA gene mutations in cancer
- SARS-CoV-2 and COVID-19 Research
- Autism Spectrum Disorder Research
- Childhood Cancer Survivors' Quality of Life
- Vaccine Coverage and Hesitancy
- Child and Adolescent Psychosocial and Emotional Development
- Pharmaceutical Economics and Policy
- Iron Metabolism and Disorders
- Global Health Care Issues
- Hemoglobinopathies and Related Disorders
- Health disparities and outcomes
- Genetic Associations and Epidemiology
- COVID-19 and healthcare impacts
- Respiratory viral infections research
- Pharmaceutical studies and practices
- Obesity and Health Practices
- Child and Adolescent Health
- Geriatric Care and Nursing Homes
- Prenatal Substance Exposure Effects
- Science, Research, and Medicine
- Biomedical Ethics and Regulation
- Global Health Workforce Issues
Cambridge Health Alliance
2024
Harvard University
2024
Cincinnati Children's Hospital Medical Center
2024
University of Cincinnati
2024
The Christie NHS Foundation Trust
2023-2024
The Christie Hospital
2023
Vaccine & Gene Therapy Institute of Florida
2023
Ohio University
2022
VCU Massey Comprehensive Cancer Center
2020
National Institutes of Health
2007-2020
Abstract Genome‐wide scans of nucleotide variation in human subjects are providing an increasing number replicated associations with complex disease traits. Most the variants detected have small effects and, collectively, they account for a fraction total genetic variance. Very large sample sizes required to identify and validate findings. In this situation, even sources systematic or random error can cause spurious results obscure real effects. The need careful attention data quality has...
To define the site of pathology in Tourette's syndrome (TS), we performed a volumetric MRI study basal ganglia structures and lateral ventricles on 37 children with this disorder 18 controls. There were no statistically significant differences size right or left caudate, putamen, globus pallidus, these populations. In contrast, there for measures symmetry putamen lenticular region. Virtually all controls (17 right- one left-handed) had left-sided predominance whereas 13 TS subjects, exceeded...
• A family study of agoraphobia (n = 20), panic disorder and nonanxious controls 20) showed the morbidity risk for all anxiety disorders to be 32% among firstdegree relatives agoraphobics, 33% patients with 15% controls. Relatives agoraphobics were also shown at higher alcohol disorders. Female found greater disorders, reflecting their increased susceptibility these illnesses, male The in was not specific but included other phobias as well. findings indicate that is a familial data may help...
Abstract Genome‐wide association studies (GWAS) have emerged as powerful means for identifying genetic loci related to complex diseases. However, the role of environment and its potential interact with key has not been adequately addressed in most GWAS. Networks collaborative involving different study populations multiple phenotypes provide a approach addressing challenges analysis interpretation shared across studies. The Gene, Environment Association Studies (GENEVA) consortium was...
Abstract To evaluate the relationship between attention deficit hyperactivity disorder (ADHD) and executive functioning (EF) a sample of ADHD children (N = 48) with above average IQs (median 117.5) was administered battery standardized norm‐referenced tests sensitive to EF. Below performance found on Wisconsin Card Sorting Test continuous test (Test Variables Attention, TOVA) but not Word Fluency or Rey Complex Figure. Significant intraindividual discrepancies were for selected pair...
Abstract Tourette Syndrome (TS) in children is associated with various neurobehavioral disorders including attention deficit hyperactivity disorder (ADHD). Children TS and ADHD show some difficulties neuropsychological tasks, but we do not know if alone have deficits. To assess specific cognitive differences among and/or ADHD, administered a battery of tests, 10 tasks related to executive function (EF), TS-only, 48 ADHD-only, 32 TS+ADHD. all groups could efficiently produce output on timed...
More than 80% of the global COVID-19–related deaths between 2020 and 2021 occurred among people aged 60 years or older, according to data published by World Health Organization (WHO) in Morbidity Mortality Weekly Report.
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning /...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning /...
Purpose To understand psychosocial outcomes after prophylactic removal of the contralateral breast in women with unilateral cancer. Methods We mailed surveys to mastectomy cancer diagnosis between 1979 and 1999 at six health care delivery systems, a smaller random sample without procedure. Measures were modeled on instruments developed assess contentment quality life, body image, sexual satisfaction, concern, depression, perception. examined associations life other domains using logistic...
Abstract: Because of recent studies showing strong prevention benefit and acceptable psychosocial outcomes, more women may be considering prophylactic mastectomy. A growing literature shows some positive outcomes for with bilateral mastectomy, but less is known about contralateral Several surveys have shown that a large majority mastectomy report satisfaction their decisions to the procedure when asked in quantitative, closed-ended format. We sought explore nuances women's using qualitative,...
About 6 million children in the US might be living with post–COVID-19 condition, also known as long COVID. A recent narrative review Pediatrics parsed existing research from past 3 years about how COVID presents and what risk factors are for developing condition.
Over the past several years, genome-wide association studies (GWAS) have succeeded in identifying hundreds of genetic markers associated with common diseases. However, most these confer relatively small increments risk and explain only a proportion familial clustering. To identify obstacles to future progress epidemiology research provide recommendations NIH for overcoming barriers, National Cancer Institute sponsored workshop entitled "Next Generation Analytic Tools Large-Scale Genetic...
Few cross-sectional studies report iron deficiency (ID) prevalence in women of different race/ethnicity and ages US or Canada.We evaluated screening observations on who participated between 2001-2003 a cross-sectional, primary care-based sample adults ≥25 y whose were complete: race/ethnicity; age; transferrin saturation; serum ferritin; HFE p.C282Y p.H63D alleles. We defined ID using stringent criterion: combined saturation <10% ferritin <33.7 pmol/L (<15 μg/L). compared subgrouped by age...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning /...
Social isolation and loneliness were associated with a 32% 14% higher risk, respectively, of all-cause mortality, as well an increased risk cancer according to meta-analysis 90 prospective cohort studies that included more than 2 million adults aged 18 years or older.
Background: Although federal legislation made COVID-19 vaccines free, inequities in access to medical care may affect vaccine uptake. Objective: To assess whether health was associated with uptake and timeliness of vaccination the United States. Design: A cross-sectional study. Setting: 2021 National Health Interview Survey (Q2-Q4). Subjects: In all, 21,532 adults aged≥18 were included Measures: Exposures 4 metrics access: insurance, having an established place for care, a physician visit...