A5092180993- Spectroscopy and Chemometric Analyses
- Spectroscopy Techniques in Biomedical and Chemical Research
- Computational Drug Discovery Methods
- Cancer, Lipids, and Metabolism
- Plasmonic and Surface Plasmon Research
- Circadian rhythm and melatonin
- Nanoparticle-Based Drug Delivery
- Dietary Effects on Health
- Metabolomics and Mass Spectrometry Studies
- Genetics, Aging, and Longevity in Model Organisms
- Viral Infectious Diseases and Gene Expression in Insects
- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
Iowa State University
2023-2024
assessment of drug response with conventional cell viability assays remains the standard practice for guiding initial therapeutic choices. However, such ensemble approaches fail to capture heterogeneities in treatment and cannot identify early markers response. Here, we leverage Raman spectroscopy (RS) as an accurate, low-cost, extraction-free, label-free approach track metabolic changes cancer cells, spheroids, organoids cisplatin treatment. We identified 12 statistically significant...
The heterogeneity of tumors and the lack effective therapies have resulted in triple-negative breast cancer (TNBC) exhibiting least favorable outcomes among subtypes. TNBC is characterized by its aggressive nature, often leading to high rates relapse, metastasis, mortality. Niclosamide (Nic), an Food Drug Administration-approved anthelmintic drug, has been repurposed for treatment; however, application hindered significant challenges, including strong hydrophobicity, poor aqueous solubility,...
Abstract The Midwest Aging Consortium (MAC) has emerged as a critical collaborative initiative aimed at advancing our understanding of aging and developing strategies to combat the rising prevalence age-related diseases. Founded in 2019, MAC brings together researchers from various disciplines institutions across Midwestern United States foster interdisciplinary geroscience research. This report summarizes highlights Fourth Annual Symposium MAC, which was held Iowa State University May 2023....