L.G. Hom

ORCID: 0009-0009-7017-0105
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About
Contact & Profiles
Research Areas
  • Insect Resistance and Genetics
  • Viral Infectious Diseases and Gene Expression in Insects
  • Bacterial biofilms and quorum sensing
  • Bacteriophages and microbial interactions
  • Protein purification and stability
  • Bacterial Genetics and Biotechnology
  • Entomopathogenic Microorganisms in Pest Control

University of California, San Francisco
2024

University of California, Berkeley
2000-2002

Invading microbes face a myriad of cidal mechanisms phagocytes that inflict physical damage to microbial structures. How intracellular bacterial pathogens adapt these stresses is not fully understood. Here, we report the discovery virulence mechanism by which changes mechanical stiffness mycobacterial cell surface confer refraction killing during infection. Long-term time-lapse atomic force microscopy was used reveal process “mechanical morphotype switching” in mycobacteria exposed host...

10.1126/sciadv.adh7957 article EN cc-by-nc Science Advances 2024-01-03
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