A5083695676- Immunotherapy and Immune Responses
- Escherichia coli research studies
- Toxoplasma gondii Research Studies
- Immune Response and Inflammation
- Nasal Surgery and Airway Studies
- Sinusitis and nasal conditions
- Inhalation and Respiratory Drug Delivery
- Pediatric health and respiratory diseases
- T-cell and B-cell Immunology
- Lymphadenopathy Diagnosis and Analysis
- Immune Cell Function and Interaction
Virologie et Immunologie Moléculaires
2003-2005
Abstract Dendritic cells (DC) are recognized as sentinels, which capture antigens in tissue and migrate to the lymph node, where they initiate immune responses. However, when a vaccine strain of green fluorescent protein-expressing Salmonella abortusovis (SAO) was inoculated into sheep oral mucosa, it induced accumulation myeloid non-DC subcapsular sinus paracortex draining SAO mainly found associated with these (granulocytes macrophages) but rarely DC. To analyze how bacteria reached nodes,...
Dendritic cells (DC) have been reported to migrate in afferent lymph the steady state. However, it is unknown whether DC traffic modulated by nature of drained tissue. To analyze influence mucosal versus cutaneous microenvironments on constitutive release, we exploited a novel technique cannulation sheep, which allowed comparison migrating from head mucosae [cervical (CerDC)] with skin [prescapular (PresDC)]. The migration rate was lower for CerDC than PresDC. Compared PresDC, contained...