A5010462481- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Traditional and Medicinal Uses of Annonaceae
- Cancer therapeutics and mechanisms
- Synthesis and Biological Activity
- Pneumocystis jirovecii pneumonia detection and treatment
- Natural product bioactivities and synthesis
- Plant biochemistry and biosynthesis
- Microbial Natural Products and Biosynthesis
- Bioactive Compounds and Antitumor Agents
- Biochemical and Molecular Research
- Berberine and alkaloids research
- Chemical Synthesis and Analysis
- Phytochemical compounds biological activities
Tongji University
2025
Hubei University of Science and Technology
2022-2024
Human immunodeficiency virus (HIV) especially HIV-1 infection and its progression to acquired immune deficiency syndrome (AIDS) remains a significant global health challenge. The advent of the highly active antiretroviral therapy (HAART) has greatly extended life expectancy patients living with HIV, but it become evident that long-term HAART will not eliminate HIV reservoir cure infection. Moreover, drug resistance undesirable side effects hamper efficacious therapy, creating an urgent need...
Acquired immune deficiency syndrome (AIDS) mainly caused by human immunodeficiency virus (HIV) type 1 (HIV-1) is a deadliest infectious disease, in which the system becomes ineffective and opportunistic infections accompany disease. Reverse transcriptase (RT) target for majority of anti-HIV-1 agents, HIV RT inhibitors can be categorized into nucleoside reverse (NRTIs) non-nucleoside (NNRTIs). In view structural diversity, unique mode action, high efficacy low toxicity NNRTIs comparison to...
Abstract Cancer is one of the most common and deadliest diseases affecting millions human beings globally. Treatment cancer has achieved great advancements, chemotherapy remains important means. However, suffers from apparent limitations including drug resistance, systemic toxicity, adverse effects, tumor recurrence, creating an urgent demand to develop novel anticancer chemotherapeutics. Furoxan derivatives could exert activity via releasing high concentrations nitric oxide (NO), which...