Jianguo Xu

ORCID: 0009-0009-8148-7407
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About
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Research Areas
  • Surgical site infection prevention
  • Reconstructive Surgery and Microvascular Techniques
  • Shoulder Injury and Treatment
  • Surgical Sutures and Adhesives
  • Advanced X-ray and CT Imaging
  • Wound Healing and Treatments
  • Shoulder and Clavicle Injuries
  • Nanoplatforms for cancer theranostics
  • Extracellular vesicles in disease
  • Tracheal and airway disorders
  • Hip and Femur Fractures
  • Nanoparticle-Based Drug Delivery
  • Radiation Dose and Imaging
  • Advanced Sensor Technologies Research
  • Cardiac Valve Diseases and Treatments
  • Dermatology and Skin Diseases
  • Infective Endocarditis Diagnosis and Management
  • Digital Radiography and Breast Imaging
  • MRI in cancer diagnosis
  • Dermatologic Treatments and Research
  • Contact Dermatitis and Allergies
  • Urticaria and Related Conditions
  • Advanced Fiber Optic Sensors
  • Bone fractures and treatments
  • Renal and related cancers

Second Military Medical University
2010-2025

Changhai Hospital
2010-2025

Lanzhou University
2022

The Third People's Hospital of Dalian City
2017

Second Artillery General Hospital of Chinese People's Liberation Army
2010

Xi'an High Tech University
2010

Alberta Environment and Protected Areas
1994

Modulating the surface properties of nanoparticles (NPs) is an important approach to accomplish immune escape, prolonged blood retention time, and enhance ability targeted drug delivery. The camouflage cancer cell membrane onto has been proved be ideal active targeting NPs. Herein, we isolated melanoma cells coat doxorubicin (DOX) indocyanine green (ICG)-loaded hollow copper sulfide NPs (ID-HCuSNP@B16F10) for photothermal therapy, photoacoustic imaging, chemotherapy. A remarkable in vitro...

10.1021/acsami.9b23177 article EN ACS Applied Materials & Interfaces 2020-03-18

Spalt-like transcription factor 4 (SALL4) plays a vital role in the progression of many human diseases. However, and mechanism SALL4 regulates keloid formation remain unclear. The mRNA levels ubiquitin-specific peptidase 37 (USP37) tissues fibroblasts were determined by quantitative real-time PCR. Western blot was performed to measure protein SALL4, USP4/10/37, collagen-related markers, PI3K/AKT-related markers. growth, invasion migration using CCK8 assay, EdU flow cytometry, transwell assay...

10.1038/s41598-025-91776-5 article EN cc-by-nc-nd Scientific Reports 2025-03-04

Background: In recent years, tumor vaccines have demonstrated unexpected success in cancer treatment. However, it still faces several challenges, including insufficient antigen and adjuvant delivery, unsuitable delivery system, inadequate antigen-presenting cell (APC) maturation. Antigenic co-delivery tactics could be one way to enhance APC Methods: Membrane-fused nanovesicles were synthesized by separating melanoma membranes from BCG cytoplasmic membranes. Dynamic light scattering...

10.3390/pharmaceutics17040507 article EN cc-by Pharmaceutics 2025-04-11

Abstract This study aimed to explore the effects of early incisional negative pressure wound therapy (INPWT) on cosmetic suture wounds and postoperative scar hyperplasia. We retrospectively evaluated 120 patients who underwent abdominoperineal resection at Changhai Hospital between February 2018 October 2021 divided them into two groups according their treatment: INPWT group (n = 60) control 60). The quality post‐surgical healing in was evaluated. Patient Scar Assessment Scale (PSAS),...

10.1111/iwj.14183 article EN cc-by-nc-nd International Wound Journal 2023-04-28

We aimed at evaluating the effects of hydrosurgery and traditional surgical approach with two parallel incisions in treatment osmidrosis.This prospective study enrolled patients axillary osmidrosis between January 2015 November 2016. For hydrosurgery, a 1-cm-long incision was made middle posterior long axis. The hand piece turned upside down processed 'W-O' way. method, 3-cm-long were transversely. Patient demographics, complications, duration procedures outcomes collected compared. All had...

10.1080/09546634.2019.1655525 article EN Journal of Dermatological Treatment 2019-08-12

To investigate the effect of magnesium isoglycyrrhizinate (MgIG) on allergy contact dermatitis (ACD) in mice.The model ACD was sensitized and challenged by 1% dinitrofluorobenzene(DNFB).48 SPF grade mice were divided into 6 groups randomly: a control group, three dosage positive group. The drug injected through vena caudalis. change ear's swelling scores thickness erythema each mouse observed. level INF-gamma, IgE, IL-4 serum detected ELISA method. Then pathologic ears using HE staining...

10.4268/cjcmm20101020 article EN China Journal of Chinese Materia Medica 2010-05-15

Objective: We aimed to introduce and evaluate the safety of double-layer-vacuum-assisted closure (DL-VAC) therapy with flap repair wound near eyes or ears. Methods: This study is case reports 2 patients who underwent DL-VAC for tissue defects The detailed process carefully described in this study. postoperative healing was closely observed. biggest concern treatment outcome on Results: Two due their soft close Both achieved primary flaps survived during follow‐up period, which ranged from 1...

10.1097/scs.0000000000009222 article EN Journal of Craniofacial Surgery 2023-02-27

Incessantly long-term real-time detection of temperature is demanded in weapon depots, where the equipment stored in, to realize self-regulation temperature. Long-Distance intellectualized control can be actualized by setting sensor-net which composed several sensors simultaneously detect multi-point and multi- parameter. The based on Fiber Bragg Grating Technology are more suitable for their preponderance high sensitivity, small volume, anti-jamming so on. sensing system, one light-cable,...

10.1117/12.866236 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2010-05-13

Embedding the Polymer fibers, whose limiting strain is about 10%, into composite materials to form intelligent researched. Encapsulating polymer fibers with epoxy resin of identical elastic modulus and embedding them structures during molding process. The Demodulating system based on F-P filter method advanced analyze shift wavelengths high speed DSP TMSC3206713 as data processor. Precise PIN photoelectric cell-InGaAs-PIN-PD753, used transform output electricity two A/D chips ADS1610 are...

10.1117/12.865499 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2010-05-13

To discuss the application of convoluted manipulation in pediatric femoral fractures.From March 2015 to October 2016, 12 children with fractures were treated by Chinese traditional including 8 males and 4 females an average age 6 years old ranging from 1 old. The causes injury falls 10 cases traffic accidents 2 cases. Of which case was transverse fractures, oblique spiral comminuted fracture, greenstick fracture. All patients underwent manual reduction within days, plus small splint cedar...

10.3969/j.issn.1003-0034.2017.07.018 article EN PubMed 2017-07-25

Objective To investigate the display ability and diagnostic value of CT enhancement MR enhanced scan in abdominal aorta branch vessels. Methods Forty-seven patients with examination underwent routine after admission Enhanced was completed within 1 week. images were analyzed by two imaging doctors more than 3 years working experience hospital. The diameter and, bilateral renal artery, superior mesenteric artery cavity measured.The measured values methods compared, Pearson correlation...

10.3760/cma.j.issn.1674-4756.2017.20.024 article EN Central Plains Medical Journal 2017-10-25

Objective To compare and quantify the differences in size-specific dose estimates (SSDE) obtained by effective diameter water-equivalent from central slice of scan range head CT examination. Methods A total 111 consecutive adult patients who underwent examination were enrolled this study. All CTDIvol values report documented. The dataset was assigned into group A B, based on individual size-dependent conversion factors (f) (deff) (dw) at multiplied normalized volume computed...

10.3760/cma.j.issn.0254-5098.2018.07.010 article EN Zhonghua fangshe yixue yu fanghu zazhi 2018-07-25

The accurate analysis of soil pore structures in thin sections depends on achieving sufficient contrast between pores and minerals. objective this research was to develop a method that requires minimum number crossed polarizer images distinguish minerals from sections. Five undisturbed samples were taken each the three soils used experiment. One section made sample. Images captured with digital video camera through microscope at X3.2 saved for later analysis. Two 0 45 degrees combined plane...

10.1097/00010694-199409000-00009 article EN Soil Science 1994-09-01
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