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S. J. Holmes

ORCID: 0009-0009-8205-2616
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About
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A5029564266
Research Areas
  • Influenza Virus Research Studies
  • Bacterial Infections and Vaccines
  • Pneumonia and Respiratory Infections
  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • HIV/AIDS Research and Interventions

Duke University
 2024

Mallinckrodt (United States)
 1992

 Immunoglobulin deficiency and idiotype expression in children developing Haemophilus influenzae type b disease after vaccination with conjugate vaccine. The Collaborative Study Group
OPENALEX - Publications 
S. J. Holmes

10.1001/jama.266.14.1960 article EN JAMA 1991-10-09
 Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques
OPENALEX - Publications 
S. J. Holmes Hui Li Xiaoying Shen Mitchell Martin Ryan Tuck and 30 more Yue Chen Elena E. Giorgi Hélène Fradin Madison Berry Elizabeth Van Italie Sravani Venkatayogi Joshua S. Martin Beem Robert J. Edwards Katayoun Mansouri Ajay Singh Cindy Kuykendall Thaddeus C. Gurley M. Anthony Moody Nicole DeNayer Todd DeMarco Thomas N. Denny Yunfei Wang Tyler Evangelous Joanne Clinton Bhavna Hora Kshitij Wagh Michael S. Seaman Kevin O. Saunders Nicholas Solomotis Johnathan Misamore Mark G. Lewis Kevin Wiehe David C. Montefiori George M. Shaw Wilton B. Williams

The details of the pediatric immune system that supports induction antibodies capable neutralizing geographically-diverse or heterologous HIV-1 is currently unclear. Here we explore environment in neonatal macaque undergoing Simian-HIV infection. infection 11 pairs therapy-naive dams and infant rhesus macaques for 24 months results 64% young compared to 18% adult macaques. Heterologous emerge by 12 post-infection macaques, association with lower expression immunosuppressive genes, fewer...

10.1038/s41467-024-54753-6 article EN cc-by-nc-nd Nature Communications 2024-11-27
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