A5102821390- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Heparin-Induced Thrombocytopenia and Thrombosis
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Muscle and Compartmental Disorders
- Sepsis Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Bacterial Identification and Susceptibility Testing
- Liver Disease and Transplantation
- Otolaryngology and Infectious Diseases
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Atrial Fibrillation Management and Outcomes
Seattle Children's Hospital
2024
Methodist Hospital
2021-2023
Services Hospital
2023
Houston Methodist
2022
BACKGROUND Fusobacterium spp. are strictly anaerobic microorganisms and normal flora of the oropharyngeal, gastrointestinal, female genital tracts. It is commonly associated with periodontal disease, pharyngitis, mastoiditis, tonsillitis, a tendency to abscess formation. OBSERVATIONS The authors report case brain abscesses complicated by ventriculitis obstructive hydrocephalus caused nucleatum suspected odontogenic source. While repeated bacterial cultures remained negative, isolate was...
An inverse relationship exists between vancomycin serum concentrations and the intensity of continuous renal replacement therapy (CRRT), reflected through dialysate flow rate (DFR). There remains a lack evidence to guide initial dosing in setting high-intensity CRRT (i.e., DFR >30 mL/kg/h). Additionally, recommendations for pharmacokinetic monitoring have transitioned from trough-based area under curve (AUC)-based strategy optimize efficacy safety. Therefore, an improved understanding impact...
We sought to examine the efficacy and safety of adding fibrinogen-guided low-dose multi-day Alteplase™ tissue plasminogen activator (tPA) in management intravascular hemolysis (IVH) patients with HeartMate II (HM-II) continuous flow (CF) left ventricular assist device (LVAD) who failed achieve IVH resolution conventional augmented anticoagulation (AAC).IVH LVAD is often treated AAC, failing which pump exchange considered. hypothesized that a trial tPA after AAC therapy could resolve prevent...
Introduction: An inverse relationship exists between vancomycin serum concentrations and CRRT doses, reflected through the dialysate flow rate (DFR). There remains a lack of evidence to guide initial dosing in setting high doses (i.e. DFR >30 mL/kg/h). Improved understanding influence on AUC/MIC has potential enhance antibiotic therefore efficacy. The goal this study is evaluate current strategies achievement pharmacokinetic targets patients dose CRRT. Methods: This was single center,...
Srour, Nina; Harris, Jesse; Succar, Luma; Salazar, Eric; Lindberg, Scott; Mobley, Constance Author Information