Cranial Fasciitis

• DOI: 10.1001/archderm.1989.01670170088016
• Publication Date: 2011-11-28T17:19:32Z
• Authors: James W. Patterson

• We present the clinical, roentgenographic, light-microscopic, immunohistochemical, and ultrastructural findings in two children with cranial fasciitis. A 7-year-old boy a 3-year-old girl presented rapidly expanding masses on scalp. Roentgenographic studies showed erosion of underlying cranium one case. Both lesions proliferations elongated spindle cells focally myxoid matrix, together areas hemorrhage, vascular proliferation, chronic inflammation. Occasional atypical nuclei were observed, but mitotic figures uncommon. Immunoperoxidase negative or equivocal staining for desmin, factor VIII-associated antigen, S100 protein, macrophage antigen. In lesion there was focal positivity α1-antichymotrypsin, another lesion, some stained positively smooth-muscle actin. Electron microscopy dilated endoplasmic reticulum, bundles microfilaments, pinocytotic vesicles, external membrane material, features myofibroblasts. excised has been no recurrence 7 years case 1 year other Cranial fasciitis is closely related to nodular fasciitis, it predilection scalp children. Despite its rapid growth, benign clinical course cured by excision without curettage bone. Our immunohistochemical observations indicate that, like represents proliferation fibroblasts (<i>Arch Dermatol.</i>1989;125:674-678)