Chronic Manganese Intoxication

• DOI: 10.1001/archneur.1989.00520460090018
• Publication Date: 2011-11-28T23:03:08Z
• Authors: C.-C. Huang; N.-S. Chu; C.-S. Lu; J.-D. Wang; J.-L. Tsai; J.-L. Tzeng; E. C. Wolters; D. B. Calne
• Keywords: Ferromanganese

We report six cases of chronic manganese intoxication in workers at a ferromanganese factory Taiwan. Diagnosis was confirmed by assessing increased concentrations the blood, scalp, and pubic hair. In addition, levels environmental air were established. The patients showed bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.