Exercise and Vitamin D in Fall Prevention Among Older Women

• DOI: 10.1001/jamainternmed.2015.0225
• Publication Date: 2015-03-23T12:34:41Z
• Authors: Kirsti Uusi-Rasi; Radhika Patil; Saija Karinkanta; Pekka Kannus; Kari Tokola; Christel Lamberg-...; Harri Sievänen
• Keywords: Contraindication

While vitamin D supplementation and exercise are recommended for prevention of falls older people, results regarding these 2 factors contradictory.To determine the effectiveness targeted training in reducing injurious among women.A 2-year randomized, double-blind, placebo-controlled open trial conducted between April 2010 March 2013 Tampere, Finland. Participants were 409 home-dwelling women 70 to 80 years old. The main inclusion criteria at least 1 fall during previous year, no use supplements, contraindication exercise.Four study groups, including placebo without exercise, (800 IU/d) exercise.The primary outcome was monthly reported falls. Injurious number fallers injured as secondary outcomes. In addition, bone density, physical functioning (muscle strength, balance, mobility), metabolism assessed.Intent-to-treat analyses showed that neither nor reduced Fall rates per 100 person-years 118.2, 132.1, 120.7, 113.1 respectively; however, 13.2, 12.9, 6.5, 5.0, respectively. Hazard ratios significantly lower exercisers with (0.38; 95% CI, 0.17-0.83) (0.47; 0.23-0.99). Vitamin maintained femoral neck mineral density increased tibial trabecular slightly. However, only improved muscle strength balance. did not enhance effects on functioning.The rate more than halved balance women, while affected Exercise functioning. Future research is needed role enhancement mobility.clinicaltrials.gov Identifier: NCT00986466.