Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival

• DOI: 10.1001/jamanetworkopen.2021.1793
• Publication Date: 2021-03-23T15:17:35Z
• Authors: Daniel X. Yang; Rohan Khera; Joseph A. Miccio; Vikram Jairam; Enoch Chang; James B. Yu; Henry S. Park; Harlan M. Krumholz; Sanjay Aneja
• Keywords: Medical record

<h3>Importance</h3> Cancer registries are important real-world data sources consisting of abstraction from the medical record; however, patients with unknown or missing underrepresented in studies that use such sources. <h3>Objective</h3> To assess prevalence and its association overall survival among cancer. <h3>Design, Setting, Participants</h3> In this retrospective cohort study, all variables within National Database were reviewed for values 3 most common cancers US who received diagnoses January 1, 2006, to December 31, 2015. The patient records assessed. Data analysis was performed February August 2020. <h3>Exposures</h3> Any field a record 63 interest more than 130 total Database. <h3>Main Outcomes Measures</h3> Prevalence cancer associated 2-year survival. <h3>Results</h3> A 1 198 749 non–small cell lung (mean [SD] age, 68.5 [10.9] years; 628 811 men [52.5%]), 2 120 775 breast 61.0 [13.3] 101 758 women [99.1%]), 158 635 prostate 65.2 [9.0] 100% men) included analysis. Among those cancer, 851 295 (71.0%) interest; 33.2% 51.6% complete (<i>P</i> &lt; .001). 161 096 (54.7%) 93.2% 93.9% 460 167 (39.7%) 91.0% 95.6% <h3>Conclusions Relevance</h3> This study found large registry–based source, there high unable be ascertained record. heterogeneous differences Improvements documentation quality necessary make optimal clinical advancements.