Assessment of Functional Mobility After COVID-19 in Adults Aged 50 Years or Older in the Canadian Longitudinal Study on Aging

• DOI: 10.1001/jamanetworkopen.2021.46168
• Publication Date: 2022-01-12T16:03:54Z
• Authors: Marla K. Beauchamp; Divya Joshi; Jacqueline McMillan; Urun Erbas Oz; Lauren E. Griffith; Nicole E. Basta; Susan Kirkland; Christina Wolfson; Parminder Raina; ; Andrew Costa; Laura Anderson; Cynthia Balion; Asada Yukiko; Benoȋt Cossette; Melanie Levasseur; Scott Hofer; Theone Paterson; David Hogan; Teresa Liu-Ambrose; Verena Menec; Philip St. John; Gerald Mugford; Zhiwei Gao; Vanessa Taler; Patrick Davidson; Andrew Wister; Theodore Cosco
• Keywords: Pandemic; Longitudinal Study

<h3>Importance</h3> The association of COVID-19 not requiring hospitalization with functional mobility in community-dwelling adults above and beyond the impact pandemic control measures implemented 2020 remains to be elucidated. <h3>Objective</h3> To evaluate between a diagnosis change physical function Canada aged 50 years or older during initial lockdown. <h3>Design, Setting, Participants</h3> This population-based cohort study used data from Canadian Longitudinal Study on Aging (CLSA) study. was launched April 15, 2020, exit questionnaires were completed September December 2020. Prepandemic first CLSA follow-up (2015-2018) also used. Respondents included middle-aged participants residing provinces. Data analyzed February May 2021. <h3>Exposures</h3> assessment for self-reported status adapted Public Health Agency Centers Disease Control Prevention case definition available at time collection; cases classified as confirmed probable, suspected, non–COVID-19. <h3>Main Outcomes Measures</h3> Changes since start assessed using global rating scales questionnaire. Participant-reported new onset difficulty 3 tasks examined. <h3>Results</h3> Among 51 338 baseline, 21 491 (41.9%) 65 26 155 (51.0%) women 25 183 (49.1%) men. Of 24 114 who questionnaire, 2748 individuals had confirmed, probable suspected COVID-19. 121 COVID-19, 113 (93.3%) hospitalized. Individuals higher odds worsening terms ability engage household activity (odds ratio [OR], 1.89; 95% CI, 1.11-3.22), (OR, 1.91; 1.32-2.76), standing up after sitting chair 2.33; 1.06-5.11) compared without same period. Similar results found (eg, activity: OR, 2.09; 1.82-2.41). <h3>Conclusions Relevance</h3> among that receiving significantly associated worse functioning outcomes even absence hospitalization. These findings suggest interventions may needed mild moderate do require