Leveraging the Expertise of the CTSA Program to Increase the Impact and Efficiency of Clinical Trials

• DOI: 10.1001/jamanetworkopen.2023.36470
• Publication Date: 2023-10-05T15:32:16Z
• Authors: Paul A. Harris; Sarah E. Dunsmore; Jane C. Atkinson; Daniel Kelly Benj...; Gordon R. Bernard; J. Michael Dean; Jamie P. Dwyer; Daniel E. Ford; Harry P. Selker; Salina P. Waddy; Kenneth L. Wiley; Consuelo H. Wilkins; Sarah K. Cook; Jeri S. Burr; Terri L. Edwards; Jacqueline Huvane; Nan Kennedy; Karen Lane; Ryan Majkowski; Sarah Nelson; Marisha E. Palm; Mary Stroud; Dixie D. Thompson; Linda Busacca; Mitchell S. V. El...; Robert P. Kimberly; Muredach P. Reilly; Daniel F. Hanley; ; Rachel Greenberg; Kanecia Zimmerman; Brian Smith; Frank Rockhold; Lori Poole; Jesse Hickerson; Eilene Pham; Eve Marion; Helen Boyle; Vincent Miller; Sonya Sutton; Michelle Jones; Princess Abbott-G...; Nichole McBee; Andrew Mould; Lindsay Eyzaguirre; Megan Singleton; Janelle Maddox-Regis; Shannon Hillery; Angeline Nanni; Meghan Hildreth; Cecilia Pessoa-Gi...; Emily Bartlett; Theodora Cohen; Cortney Wieber; Krista Vermillion; Erin Rothwell; Kevin Watt; Kathy Sward; John M. VanBuren; Mary Pautler; Marie Kay; Jordan Bridges; Krista Ellis; Francis Sebahar; Eun Hea Unsicker; Valeriya Vasenina; Talmage Morris; Michelle Aponte; Ann Johnson; Annie Risenmay; Lisa Rigtrup; Gary Henderson; Ammon Leon Pate; Monse Lopez; Leslie Boone; Loretta Byrne; Tara Helmer; Maeve Tischbein; Leah Dunkel; Stephanie Mayers; Kaysi Quarles; Jasmine Bell; Bridget Swindell; Jabari Ichimura; Devan Ray; Caitlin Rantala; Jessica Eidenmuller; Emily Serdoz; Natalie Dilts; David Crenshaw; Brooklyn Henderson; Meghan Vance; Delicia Burts; Dione Grant; Jahi Hamilton; Matt Schorr; Colleen Lawrence; Meredith Bernui; Taylor Budine; Amna Baig; Joseph Christodoulou; Jodie Cohen; Tiffany Chen; Julia Dunagan; Wendy Lloyd
• Keywords: Translational Research; Translational Science

Multicenter clinical trials play a critical role in the translational processes that enable new treatments to reach all people and improve public health. However, conducting multicenter randomized (mRCT) presents challenges. The Trial Innovation Network (TIN), established 2016 partner with Clinical Translational Science Award (CTSA) Consortium of academic medical institutions implementation mRCTs, consists 3 Centers (TICs) 1 Recruitment Center (RIC). This unique partnership has aimed address roadblocks impede design conduct expectation accelerating translation novel interventions practice. TIN's challenges achievements are described this article, along examples innovative resources may serve as useful models for other trial networks providing operational recruitment support.