Using the Wash U Epigenome Browser to Examine Genome‐Wide Sequencing Data

• DOI: 10.1002/0471250953.bi1010s40
• Publication Date: 2012-12-19T18:28:49Z
• Authors: Xin Zhou; Ting Wang
• Keywords: Genome browser; Epigenome; Upload; Epigenomics; ENCODE

Abstract This unit describes the Wash U Epigenome Browser, a next‐generation genomic data visualization system. The Browser currently hosts ENCODE and Roadmap Epigenomics for human model organisms. displays many sequencing‐based sets across all or part of genome, on specific gene pathways, in context their metadata. Investigators can order, filter, aggregate, classify, display interactively based given feature including metadata features, annotated biological user‐defined collections genes coordinates. Further, statistical tests be performed selected data. Individual labs upload sequencing array‐based as custom tracks them consortium data, allowing direct comparisons. is an increasingly important widely accessible tool deriving insights from unprecedented amounts high‐quality genomic, epigenomic, expression Curr. Protoc. Bioinform . 40:10.10.1‐10.10.14. © 2012 by John Wiley & Sons, Inc.