Imaging with Optogenetically Engineered Living Cells as a Photodetector

• DOI: 10.1002/adbi.201800319
• Publication Date: 2019-06-21T08:34:09Z
• Authors: Gongxin Li; Feifei Wang; Wenguang Yang; Wenxue Wang; Guangyong Li; Yuechao Wang; Lianqing Liu
• Keywords: Photodiode; Living cell; ENCODE

Abstract Biosyncretic systems integrating biological components with electromechanical devices have recently become a promising technology, in which are used as actuators or sensing elements higher‐level performance than artificial systems. Here, biosyncretic imaging system using an optogenetically engineered living cell photodetector is shown. The photoresponsive properties of the cell, such spectrum and response range, dynamic characteristics, measured indicate that functions excellent photodetector. In system, directly utilized to generate light‐triggered ionic currents, encode spatial image information therefore reconstruct scenes under view based on compressive sensing. Imaging cell‐based successfully performed by acquiring high‐definition images system. also displays function superiority commercial photodiode, wider responsivity range. This work represents step toward materials paves new road for development future on‐body bionic devices.