Advances in Bioadhesive Hydrogels for Musculoskeletal Tissue Application

• DOI: 10.1002/adfm.202316540
• Publication Date: 2024-05-02T02:53:50Z
• Authors: Fang‐Xue Zhang; Meng‐Han Chien; Qing‐rui Fan; Dong Jiang
• Keywords: Tissue Repair

Abstract The musculoskeletal system, which is responsible for weight‐bearing, movement, and organ protection, faces many disorders arising from injuries, diseases, trauma that affect millions of people worldwide, resulting in a decreased quality life socioeconomic burden. Tissue engineering at the forefront current research on tissue regeneration demonstrates great potential repair. Among numerous grafts available, adhesive hydrogels have demonstrated applications. Despite surge development bioadhesive hydrogel formulations recent years, absence an evaluation protocol their formulation has led to emergence similar products do not fully meet clinical requirements applicability regeneration. This review aims address this gap by first discussing design considerations ideal relevant successful By thoroughly reviewing advances hydrogels, with particular focus applications facilitating repair, improvements are proposed criteria novel applications, several key challenges directions implementation summarized.