Dual Functional Z‐Scheme Heterojunction Covalent Organic Frameworks for Bipolar‐Driven Organic Photoelectrochemical Transistor Biosensing

• DOI: 10.1002/adfm.202424871
• Publication Date: 2025-03-11T15:18:42Z
• Authors: Jia‐Hao Chen; Xuan Wang; Hongtao Chen; Degang Jiang; Jing Liu; Hong Zhou
• Keywords: Covalent organic framework; Photoelectrochemistry

Abstract Organic photoelectrochemical transistor (OPECT) as a photo‐electric‐biological technology, is shown considerable potential for high‐performance detection in biological sensing. High gating effect and current always pursuit to improve the performances of OPECT, but date, their inherent channel materials invariant structure limit further development. The challenge addressed through new bipolar‐driven OPECT signal amplification efficient modulation. Herein, inspired by self‐powered (PEC) systems, enhancement‐mode poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) powered Z‐scheme COF/Cu 2 O@Cu PtNCs photocathode CdIn S 4 photoanode proposed. It exhibits an enhanced remarkable gain ≈7613, which much higher than single‐photoelectrode ones will have beneficial impact on achieving sensitive, portable, reliable sensing devices. Moreover, sandwich system composed multifunctional COF‐based nanomaterials target‐mediated biomimetic precipitation reaction designed upon photocathode, resulting dual realizing alpha‐fetoprotein (AFP) with linear range 32 fg mL −1 –10 ng low 22 .